Turning Healthcare AI from Vision to Verified Impact with Pegasus One
24m 41s
Charter Health and Pegasus 1 collaborate to build an autonomous AI platform that enables hospitals to analyze unstructured and siloed healthcare data—such as EMR, lab, and financial records—to generate actionable insights in real time. The platform addresses critical challenges like data latency, interoperability, and workflow disruptions using the Song Framework: Signal (data availability and timing), Orchestration (workflow integration), Normalization (standardizing clinical data), and Governance (regulatory and operational compliance). Pegasus 1’s deep expertise in healthcare standards and data systems ensures technical feasibility and long-term resilience. Charter Health’s vision goes beyond analysis to deliver real-world impact—reducing sepsis rates, improving patient outcomes, and enabling proactive regulatory compliance. By automating data analysis and minimizing manual effort, the platform compresses research timelines from weeks to minutes, enabling faster decision-making. As usage grows, the system learns from diverse hospital practices, creating compounding intelligence and workflow efficiencies. Crucially, the solution avoids overburdening clinicians by delivering high-confidence insights and minimizing human-in-the-loop requirements. Ultimately, the partnership emphasizes that successful healthcare AI hinges not on intelligence alone, but on robust, sustainable foundations that align with real-world clinical operations and data realities.
Welcome to the AI-Advive series on the BEAT Podcast, where we dive into the artificial
intelligent solutions that are driving automation, generative, and agentic AI in the healthcare
space.
Follow this series to develop the skills you need to evaluate use cases, plan your next
move in the world of democratized experimentation, and stay in the know on the latest AI technology
breakthroughs.
And now, your host, Sandy Vance.
Hey, everybody. Welcome back to the AI series on the BEAT. I'm your host, Sandy Vance.
And today, we're here with Pegasus 1, Tushar Piri is the CEO and founder of this services
organization that has been around for about 15 years. Welcome to the show Tushar.
Thank you, Sandy Vance. Great to be here.
And we are delighted that today Tushar has brought one of his clients, Sebastian Uslas, who
is the co-founder of Charter Health.
Sandy, excited to be here with everybody?
Sebastian is a technical co-founder of Charter, and they have been developing a platform technology
that Tushar's organization has helped with. So we're going to get into a deep dive of
how they're building the secure and scalable AI platform. But first, Tushar, can you just
tell me a little bit about Pegasus 1 and where you started?
Pegasus 1 is a healthcare focused technology and product engineering partner. But since
the inception, I never considered us to be a company who is just providing services
in building products because we realize and we realize it every day that for building
a solid product, companies like us need to understand business as well as our customers
too. And then look into the product development more from owners perspective. And that's what
we bring to the table for each and every offer implementation, especially in healthcare,
sadly, about 80% of AI initiatives do not make it to production. And we have seen the
reasons most of these implementation do not make it to production are predictable. And
they are generally ignored, such as aspects like interoperability or data latency, which
are generally coming in as afterthought. And workflow and integrations are generally
underestimated or ignored. So we have essentially codified these aspects which can make a project
to not succeed in what we call as a song framework. So when we work with any in every client,
not only that we focus on their core problem or the initiative they are trying to build,
but also ensure from day one that they don't into this pitfalls. So we are building with
the end in mind always and ensuring that their product is indeed in a position to go to
market beyond POC. Tell me more about this song framework. Song framework stands for as
for signal, which we will call the data aspect orchestration stands for the workflow aspect.
Normalization is normalizing the data, you know, as you know, same medication is written
differently by different doctors and facility. Similarly, lab results, even imaging results
for same kind of scan are coded differently. So for a company like charty, all these aspects
need to be normalized so we can get more coherent outcomes. And then G stands for governance,
which as you know, it's obvious because for any and every implementation governance
need to be baked in from day one. So when we look at a problem or a project, we ask these
questions asked to ourselves and also to our clients, every thought through the data aspect,
the orchestration, which is will it work in the workflow, which clinicians are already
using or you're expecting to change their daily routine, which means it is better how good
your AI is. It's not going to be very successful if you're asking clinicians who are already
overburdened over work to change their day to day work. And normalization is obvious,
you know, especially for project product like charty, we are working with humongous amount
of data and we need to make sure if all the data pieces are normalized and they talk
and mean same thing, then getting lost into translation of the various system, then governance
has to be the part of the whole application. So we can identify ever changing ecosystem
of healthcare and we know what's changing, why it's changing and we can explain it and
continue to build the trust of our clinicians. Fantastic. I love a good acronym. I think
that is such a cool way to sort of make sure that you hit all of the things. So Sebastian
is the technical co-founder of Chardar as we discussed and he's been working on shaping
the platform's technology vision and architecture. So tell our audience what is this application
that you're trying to build or is it a platform you're trying to build, how you got involved
with Pegasus 1 and how they've helped aid in your mission.
The vision of Chardar Health overall is to be able to allow hospitals and then health
systems to use their data across different data silos. So think unstructured data in your
EMR, different data systems that they have, financial data and leverage that to kind of
generate analytics and understanding from that. So an example that we like to use is lots
of hospitals care a lot about their sepsis rates because CMS oftentimes penalizes hospitals
based off of their sepsis rates and they try to really understand what's driving those
sepsis rates to be bad and then really work at addressing those issues to be able to fix
it to be able to kind of deliver higher quality of care for patients as well as reducing
those fines from CMS. And a lot of the time the work that they do to do that is they're
higher in consultants to really go in, look at the data, analyze and understand what's
happening with that data. But those things can take quite a long time and it can take
months or partially up to a year to be able to understand and analyze that data and then
they have to go in and actually implement those changes. What we're working at at Chardar
Health is a system to be able to allow these hospitals to continuously analyze and understand
the information that they have across their different data silos. And what we're doing
directly with Pegasus 1 is building out a product called Chardar, which is a autonomous system
that allows you to take that data and ask a question similar to how you'd ask Chatchee
BT or ask kind of cloud or things like that to be able to say from this data that we have
about these different patients, what are some kind of questions that we'd like to ask
and then generate those answers. So as an example, one of those things is saying for these
different patients, what's their right of sepsis? And then we can ask even more complicated
questions from there like what are some factors that correlate to these sepsis cases? As
an example, maybe these patients were seen in a certain department of the hospital and
that correlates quite heavily with these kind of increased rates of sepsis. And those
types of things are things that people within the hospital, within their data departments,
are doing already. And they're truly trying to understand that. And we're really working
on giving them a system and a platform to do that automatically without having to basically
take the data out of those silos and then put it into Excel and in all these different
places, which can take quite a lot of time and they don't really have yet a unified system
to be able to do this type of analytics. And that's really kind of the goal with what
we're building. Fantastic. So what made you decide to partner with Pegasus?
Yeah. So Pegasus one was one of the kind of best people that we found in terms of both
their understanding of kind of healthcare interoperability standards in terms of kind
of fire HL7 as well as kind of how those systems work in general. We as our team did not
have as much of kind of a technical background on that side. Our expertise is more so on
that kind of clinical data processing, processing unstructured tech side of things, as well as
kind of the AI agent side of things and really kind of what we saw from Pegasus one was
quite a lot of expertise when it came to interoperability as well as kind of how we can
think about those kind of solutions that we were thinking about long term. As Tushara
had mentioned, they really worked with us to understand, okay, what is it that you guys
are trying to do? What is it we're trying to develop? And then is that feasible with
those technologies that exist within the healthcare world? And we work directly with them
to answer a lot of those questions that we had in terms of kind of applications of AI
to these places. What's that data that we can get from the different smart on fire APIs
and things like that? So they've been a great help when it came to kind of setting the
direction for our technical side of our product and really help us understand what is feasible
and what's kind of capable within those healthcare settings.
Fantastic. So Tushara, you mentioned earlier that a lot of AI projects fail. Obviously Pegasus
one works with organizations. You want them all to succeed. Do you sort of have to make
decisions going into projects like Sebastian presented to you to figure out if they're
going to be able to make it or not? Do you think you can make any project work? What makes
the determining factor on whether or not you guys can help an organization a startup like Sebastian's?
working with, get the job done.
The hardest part of Health Care AI isn't the intelligence aspect.
It's surviving the contact with reality.
The projects that make to the production are designed around
the real healthcare systems.
So by real healthcare systems,
I just don't mean the workflows which clinicians go through,
but also managing the data.
We all know one way or the other, we can get the data,
but are the systems being built around latency of the data
or missing pieces of the data?
Because you know, all the systems work on different schedules.
Some might have 30 minutes delay,
some might even have overnight delays.
So are the systems engineered well enough
that they can handle those delays?
And also in some cases, if they don't get the data,
will they be able to manage their workflows and the outcomes?
So that's where the, the S aspect,
the signal aspect comes in.
Do we have NF data?
Do we have enough availability of data?
Do we know the cycle in which we'll be able to find the data?
So those are important things and co-founders.
They need to understand that, okay,
if I have to build this system which runs on data,
if we get the data, we all know AI can run.
But all the back-end aspect we need to happen
to get the data and also account for lack of data
is very important.
And then once we have built a solid rail of data pipeline,
then we do also figure out how it fits in with the workflow.
How much changes are overburdened and overworld,
clinicians have to change in their day-to-day life
to get insights out of this application.
And if it's too many changes,
we know it's not going to be very successful or very well adopted.
Other aspects which we have seen where product struggle
are companies not realizing the budget data to keep in mind
after products have gone live.
You know, first few iterations of going live,
which needs to account for what we call as agent drift.
You know, given how fragmented
and dynamic healthcare systems are,
ecosystem is changing every day.
ICD course change, regulations change,
formularies change, you know,
the lab standards change,
which means there needs to be an ongoing
and continuous monitoring of the performance
of the CI systems and tweaks are needed.
So we need to manage that agent drift
as proactively as possible,
which means not only building systems
around it, but accounting for the cost for it.
Also, we all know everybody is very,
everybody wants to implement AI,
but we also need to make sure when we're implementing AI,
it's not adding more homework
by bringing human in loop, you know,
we all know he bringing human in loop is important,
but we need to be very considerate about the fact
how much and when.
So if the outcomes which we are getting
are of high confidence and they are well-sourced,
maybe we need to build workflows
that they can just pass through
without bringing human in life,
human in the loop.
In healthcare, we are focusing on what problems
we can solve with the power of AI models or the data I have,
but the song framework is,
I consider as analogy to the non-functional aspect
that for your product to be successful,
make sure you're understanding your data,
not just what data you're getting,
but the format you're getting in,
what kind of normalization you need,
what kind of changes it can have
because of regulations or plans changing
or formularies changing or ICD course changing,
and also make sure you know how the workflows
which are using it,
what would be their needs for governance or reporting
or how it will help the clinicians who are using it.
So they are not challenged by the outcomes,
they feel supported by the outcomes.
Sebastian, could you just talk about
how this is enabled the foundation of Charity
to just be solid?
I mean, I'm sure it's a co-founder to your point earlier.
Like this integration piece is not the strength
of the sort of core capability of Charter.
And so having this sort of ally to Char's been in this
for 15 years, like you said earlier,
they know HL7 fire,
they've got those guard rails for you
to sort of just stabilize your foundation.
Like can you talk about what that's done for you
as a co-founder and enabling you
to take the vision of Charity out into the industry?
What the kind of partnership between Charter Health
and Pegasus One really enables is it allows us to,
I think from my perspective,
really achieve our vision more thoroughly.
I think there's quite a lot of different people out there
that work on a variety of different things
and are really great experts at things.
I don't think you always need to reinvent the wheel
in every single aspect, right?
Like for Charter Health,
we want to be really, really great at delivering
these insights and analytics across these health systems
and hospitals to be able to really kind of influence
the way that these hospitals work, right?
And for that, there's so many other components
that are kind of foundational pieces
like understanding how this interoperability works,
like understanding data governance,
like being able to make sure that agents
don't drift over time.
And I think those are all things that you can leverage
other organizations and the expertise that other people have
and have developed over time to be able to help you
operate to a full capacity.
And I think that's something that Pegasus One
has allowed us to do.
- Too short, like as so now you've got this foundation laid
for Charter and Charter is launched and it's live
and you guys are working well together.
What benefits do you anticipate moving forward
as Charter maturers and maybe scales into a bigger thing?
- I would say as Charter scales for good or bad off it,
it will bring new problems, which are great
because so first of all, as it scales in my opinion,
the immediate benefit for the users
would be the time compression.
So the research questions that are currently taking
several weeks, somebody has to do data wrangling,
they are exporting information to Excel,
cleaning it, reformating it,
and then running the analysis that timing should collapse
from days to hours or minutes.
So it will eliminate the friction between what insights
I can get from this data to let me further explore
the insights which I got from Charter.
So long term, I think the benefit is
what I would call compounding intelligence.
You know, every Charter, every query with Charter handles,
every co-authored bills, every analysis it runs,
it becomes institutional knowledge.
And as the patterns in image, future data preparations
would be fast.
So like the example Sebastian was mentioning,
once they have done 100 subsistence analysis,
the 100 one will be much faster and much more efficient.
And that benefit will go to the researchers
and the users of the application.
And then will, I will say,
we'll have a workflows multiplier effect.
So since it's becoming more and more better and faster,
so you need now less people doing low hanging work
of data wrangling, data cleaning and massaging
and being able to get more insights out of the data
using Charter.
Lastly, but I believe it's the most important thing
which it would matter is the bottom line
of the health systems, you know.
So there's a compliance and quality angle to it.
If Charter can help identify quality metrics
proactively and surface cohorts
for regulatory reporting automatically,
that's just not efficiency.
That's revenue production and risk reduction
for our health systems.
And I believe that's one of the most important thing,
you know, health systems can extract out of Charter
in addition to the insights.
- So Charter's got a big vision for you Sebastian.
What about you?
What are you most excited about as you move forward?
- I really like the Charter vision.
I think it aligns kind of quite well with what we were seeing
and kind of what our long term vision is for Charter Health
and Charter as well.
I think another thing that I wanted to mention was,
there's kind of a term that gets thrown around,
which is network effects, which is basically saying like,
the more people you have on a system, the better,
the system works for a lot of other people.
And maybe you might see kind of a system like Charter
as kind of individual people are using it
and kind of individual hospitals are using it,
but really kind of going back to Tishar's point,
the way that we have it set up is it's able to learn
and iterate and improve from those kind of individual processes
and individual analyses that are run
across these different institutions, right?
And the more people you have running these analyses,
the more kind of understanding you have from these different
kind of ontologies that we have added in,
these different. expertise that we have brought in from these different hospitals.
Like, as we know, different hospitals have different ways that they like to do their own
analytics.
It's not kind of as much as we like to say, like, sepsis is the same across all hospitals.
Every different hospital has different ways that they do their analytics, their understanding,
their insights.
All right.
And the more exposure we have as an organization to the way that those are run, the better
we can really kind of refine the analysis that occurs, right?
So I think to go back to to Charles Point, the more the more occurrences that are run,
the better the system operates and kind of the faster it's able to do that.
The more accurate it is as well, what at the end of the day, Charter's goal is to really
improve the quality of care across these institutions and these hospitals.
And if we can really deliver those insights faster, then we're able to allow hospitals
to implement those changes across their across the hospital more effectively, right?
And I think one thing that I like to say sometimes is when you're, when these hospitals
are doing these analyses, oftentimes they're doing the analyses on data that's multiple
months old, right?
They'll start a higher, some consultants in and those consultants will look at data from
a few months ago.
So let's say as an example, from November of 2025, and like right now it's, it's February
of 2026.
Within those four months, a lot of the people that are those cases of sepsis have either
potentially left the hospital or are sometimes have died, right?
And those changes that you're implementing are lagging kind of on that data that you
have.
And I think to be able to enable a hospital to say we currently have these 100 patients
that are potentially either facing sepsis or we see that if we change these factors,
we can potentially reduce their risk of mortality by 50%.
Those end up being live-safed, right? And when you're looking at that data retrospectively,
those people might not be around anymore, right?
And if you're able to do that over the patients that were here in the last two days, then
you can really make an influence on unsaving those people's lives.
And I think at the end of the day, that's really kind of the goal for a lot of us.
I think that's for why a lot of us go into healthcare, that's why a lot of us kind of
are really working on the problems that we're working on as much as they are kind of interesting
and great technical problems. I think at the end of the day, a lot of us kind of care
about delivering better quality of care for patients, right?
And I think the goal of Charter is as kind of Charter grows and as kind of Charter Health
grows and continues to have our partnership with Pegasus 1 is really at the end of the day
working towards that.
I think the future of healthcare really depends on founders like you innovating Sebastian.
So thank you for what you're doing. I can't wait to see what Charter Health does with the
support, of course, of Pegasus 1. And I'll just ask to Charter, before we part, do you have
any final thoughts for our audience?
I would say every founder, and I'm talking even when they're trying to find a service
where they need to be prepared enough to not only just focus on what they're building,
but everything around it is more important because unfortunately, I've seen several clients
reach out to us who have built great products but flimsy foundations.
So when they, when any founder is finding trying to find a service organization to build
their product, make sure they understand all the important aspects of a strong product
which can make them successful. And it will be different industry by industry to some
extent.
There are some overlaps, but those foundational pieces are very important.
Sounds advice. Well, thank you guys both so much for your time today.
Always a great conversation. I look forward to seeing your presentation at the Vive event
in the AI zone. And for more information on Pegasus 1, you all can go to Pegasus1.health
for Charter Health. You can go to Charter Health at CHRTRHELTH.com. We'll put both of those
links in the show notes to make it easy for you. And I hope that you all have a fantastic
day.
Podcast Summary
Key Points:
Pegasus 1 offers a healthcare-focused product engineering partnership with a proven framework to ensure AI projects survive in real-world clinical environments.
The "Song Framework" (Signal, Orchestration, Normalization, Governance) systematically addresses data integrity, workflow integration, and clinical adoption to prevent project failure.
Charter Health builds an autonomous AI platform enabling hospitals to analyze fragmented data across silos and generate real-time insights—such as sepsis risk—without manual data wrangling.
Pegasus 1’s deep expertise in healthcare interoperability (e.g., HL7, FHIR) and data governance was critical in shaping Charter’s technical feasibility and long-term scalability.
The platform accounts for data latency, missing data, and regulatory changes through continuous monitoring to manage "agent drift" and maintain model accuracy over time.
Charter’s vision includes compounding intelligence, where repeated analyses build institutional knowledge, improving future query performance and reducing time-to-insight.
Network effects and real-time analysis allow the platform to learn from diverse hospital practices, enhancing accuracy and enabling proactive quality and compliance improvements.
Success hinges not just on AI capabilities but on foundational aspects like data availability, workflow impact, and clinician trust—ensuring solutions are sustainable and adoptable.
Summary:
Charter Health and Pegasus 1 collaborate to build an autonomous AI platform that enables hospitals to analyze unstructured and siloed healthcare data—such as EMR, lab, and financial records—to generate actionable insights in real time. The platform addresses critical challenges like data latency, interoperability, and workflow disruptions using the Song Framework: Signal (data availability and timing), Orchestration (workflow integration), Normalization (standardizing clinical data), and Governance (regulatory and operational compliance). Pegasus 1’s deep expertise in healthcare standards and data systems ensures technical feasibility and long-term resilience.
Charter Health’s vision goes beyond analysis to deliver real-world impact—reducing sepsis rates, improving patient outcomes, and enabling proactive regulatory compliance. By automating data analysis and minimizing manual effort, the platform compresses research timelines from weeks to minutes, enabling faster decision-making. As usage grows, the system learns from diverse hospital practices, creating compounding intelligence and workflow efficiencies.
Crucially, the solution avoids overburdening clinicians by delivering high-confidence insights and minimizing human-in-the-loop requirements. Ultimately, the partnership emphasizes that successful healthcare AI hinges not on intelligence alone, but on robust, sustainable foundations that align with real-world clinical operations and data realities.
FAQs
The Song Framework (Signal, Orchestration, Normalization, Governance) ensures AI projects in healthcare are built with real-world constraints in mind. It addresses data availability, workflow integration, data standardization, and ongoing governance to increase the likelihood of successful production deployment.
Many AI projects fail due to overlooked issues like data latency, interoperability gaps, workflow disruptions, and lack of governance. These foundational problems are often addressed only after the initial development phase, leading to poor adoption and failure in real-world settings.
Charter Health builds an autonomous AI platform that allows hospitals to analyze data across silos—like EMRs and financial systems—by asking natural language questions, such as 'What are the sepsis risk factors?' to generate actionable insights automatically.
It reduces time spent on manual data analysis from weeks to minutes, enables real-time insights, and helps identify trends that can improve patient outcomes, reduce sepsis rates, and meet regulatory compliance more efficiently.
Pegasus 1 provided deep expertise in healthcare interoperability standards (like HL7/FHIR), data governance, and system scalability—critical areas where Charter Health’s technical team lacked experience and needed trusted guidance.
As usage grows, the system develops 'compounding intelligence'—becoming faster and more accurate with each analysis—and reduces the need for manual data work, leading to better clinical decision-making, improved compliance, and reduced patient risk.
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