The narrative around testosterone has surged online, fueled by influencers, celebrities, and social media claims that supplementation boosts energy, libido, and masculinity. While science confirms that testosterone can help men with clinically low levels improve muscle strength and sexual function, it does not universally enhance energy, aggression, or overall well-being. Studies show that in healthy individuals with normal testosterone ranges, supplementation offers no significant benefits. For women, especially post-menopausal women, testosterone can improve sexual satisfaction, but results are modest. Major risks include infertility due to suppression of natural hormone production and potential cardiovascular issues. The cultural obsession with testosterone often stems from marketing, unrealistic body ideals (like those in toys or media), and a broader societal shift toward narrow definitions of masculinity. Experts emphasize that testosterone is not essential for health, happiness, or vitality—what matters most is self-acceptance and physical well-being. The science suggests young men do not need testosterone to succeed or feel good; instead, they benefit from reassurance, support, and a healthy relationship with their bodies. This episode calls for critical thinking over hype, urging listeners to separate scientific facts from influencer-driven myths.
Should you take testosterone?
Hi, I'm Wendy Zuckerman, and this is Science Versus.
All over the internet, people are saying that you need to be thinking about your testosterone.
Taking tea used to be something mostly done by bodybuilders, but now it's pretty mainstream,
with prescriptions for tea going up more than 10 times over the last two decades.
That's according to an analysis from the New York Times.
And our obsession with testosterone reached new heights when earlier this year,
U.S. Defense Secretary Pete Hexeth announced that he wants to screen soldiers for low testosterone
in order to create a high-tea department of war.
Why?
As we know, the modern battlefield is brutal and unrelenting.
It requires and demands maximum psychological and mental readiness.
And online, you'll hear that we're in the midst of a testosterone crisis,
with tea levels apparently plummeting among men, who say that it's making them miserable.
There's tons of videos out there where young guys give each other tips
on signs to look out for to show that your testosterone is low.
You get anxious out of nowhere, you can't grow facial hair,
you stop caring about a lot of things, and you're awake at 3am every single night.
Influencers tell us that women need to be thinking about their testosterone,
especially after menopause.
And loads of folks, including celebrities like Joe Rogan and Halle Berry,
swear that once they took extra testosterone, their life got better.
They say their sex life improved, they felt stronger and more energized.
"Yeah, it makes a big difference. F**k yeah."
"My brain fog basically disappeared. My libido came back."
"I actually feel like a man. I don't let s**t slide.
I feel like I have a lot more work ethic, more motivation,
and I just want to keep going."
"I just want to beat my s**t all day."
Many women tell me they have better focus,
they feel like they want to do more things than they did before,
and they finally feel like themselves again.
So what is going on here?
Should we all be worrying about testosterone and taking a little tea on the side?
Or is this toxic masculinity on, well, steroids?
When it comes to testosterone, there's a lot of. "I just want to beat my s**t all day."
But then, there's science.
Science versus testosterone is coming up.
If you have a testosterone-curious friend, share this episode with them.
Let them know the real science on testosterone.
Which is coming up after the break.
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Welcome back today on the show, The Science of Testosterone.
Been in the news a lot recently and all over social media to tell us all about it.
We have, of course, the beefiest, buffiest science journalist, senior producer, Rose Rimmel.
Hi, Wendy.
Hi, Rose.
Let's just jump in.
And let's look at the biggest, literally the biggest claim out there about testosterone,
which is, can it make you stronger?
Bigger muscles, stronger.
Bigger muscles.
That's right.
That's right.
Which, you know, lots of people want right now.
Could it help?
So I talked about this with a scientist who specializes in studying testosterone.
In fact, Wendy, he's responsible for some of the seminal research in this space.
Was that a pun on semen?
Yeah.
Yeah.
Yeah, I got it.
Good, good, good.
I'm Shalinder Basin, and I'm professor of medicine at the Harvard Medical School.
Shalinder said that early in his career, there was actually a big debate among scientists
about this very question.
Whether taking testosterone actually does make you beefier or more athletic.
So on the one hand, you had athletes that were getting into trouble for taking anabolic
steroids, which are basically like souped-up derivatives of testosterone.
They're also sometimes called androgens.
So take the famous case of an Olympic runner named Ben Johnson.
This was in the late 1980s.
He was a sprinter, had a record, broke the records, and he was using anabolic steroids.
He admitted to it, was disqualified.
But it was all over the news.
Rumors have persisted about Johnson, who said staggering,
records in the past 18 months.
Now those rumors appear to be confirmed.
The implications are enormous.
It's a very sad day, you know, for athletics as a whole.
So even back then, they knew testosterone could make someone a faster runner.
That's why you weren't allowed to take it, right?
It's funny, like, in the sports world, that was believed widely, so much so that the Olympic
Committee was like, no, no, you can't take that.
It's not fair.
It's not fair.
But in the sciences?
In the science world, it was not yet widely accepted that this was even true.
So Schellender brought up the case of Ben Johnson because, you know, this was in the
80s.
He was sort of beginning his career, and that made a big impression on him because that
same year that Ben Johnson was disqualified for using a steroid, there was this paper
that came out by a respected endocrinologist that said. There's no evidence that androgens have anabolic effects.
They increase muscle mass or strength or performance.
The implication being that people who are abusing anabolic steroids are misguided.
There were some studies that looked at this and found they often didn't really find an
effect, but people in the, you know, the world of athletics, they would look at these studies
and they'd be like, "Well, yeah, you didn't use a high enough dose.
This is not the dose that we would expect people in the bodybuilding community, for example,
to use."
Uh-huh.
So Schellender and some colleagues, they wanted to get to the bottom of this.
They wanted to get to the bottom of this question.
So they designed this great study.
So they gave big doses of testosterone to healthy men.
These were guys in their 20s and 30s.
They got about 40 people.
Some of them got testosterone, but some of them got placebo.
And they also had some of the guys lift weights and some of the guys didn't do any exercise.
This went on for 10 weeks.
Meanwhile, they were, like, monitoring the guys' diets.
Making sure they were eating about the same number of calories, same protein.
So it was—
Yeah.
It was pretty thorough.
Yeah.
And they were checking to see, at the end of the 10 weeks, did people's muscles
get bigger?
Could they lift more weight?
Surely.
It must work.
Well, here's what happened.
Okay.
So, first of all, everybody who weight trained saw an improvement.
They got bigger and stronger.
Not too surprising.
Great.
Thank you.
But the effect was a lot bigger for the guys on tea versus the guys on placebo.
So, they had been doing stuff like squats with barbells, and at the end of the trial,
they could squat—the guys on tea could squat 40% more weight, while the guys on placebo,
only 20% more.
Yeah.
Yeah.
That's right.
I mean, you—I know it's so hard to know what's real and what's not, but you—there's
a whole concept in weightlifting around whether you're juiced or whether you're natural.
Yeah.
And you see these guys, and so clearly juiced up with testosterone.
Yeah.
But— But—
I'm not here to tell me that this is all placebo.
I mean, I—
That would be wild.
Right.
so it is real
it's real
and even the guys
that didn't do
any weightlifting
but were on T
saw gains
they
you know
they sat on their asses
for 10 weeks
but took T
they actually put on
slightly more muscle
than the guys
who went to the gym
and lifted weights
but were on placebo
but were not
oh
not taking testosterone
wow
that's how good it is
which is totally unfair
totally unfair
mmhmm
so
Schallender and his team
they wrote all this up
and put it in a paper
it was published
in the New England Journal of Medicine
July 4th
1996
and it
immediately changed
the academic view
after that
nobody has ever
questioned this
yeah
and since then
there have been
plenty of other studies
showing this
and showing that
you don't have to be
a cis man
for this to work
researchers have also shown
that adult women
who take T
will put on muscle
as well as transgender men
and do we know
exactly how
it works
how is
testosterone
stimulated
muscle growth
so we know
that the testosterone
will actually tell
your stem cells
to become muscle cells
mmhmm
and so
that turns them
into the fibers
that make up
your muscles
they literally get
thicker
because of this
that's crazy
it really does work
testosterone
now I'm guessing
we're gonna talk about
the risks
later in the show
no
that's the end
of the episode actually
great
go for it
live your dreams
hack your muscles
but yeah
but before we get to the risks
let's
look at some of these
other claims
okay
so the next one
I want to talk about
is the idea of testosterone
making you more aggressive
um
because a lot of guys online
when they talk about this
they make it sound like
you're gonna go from like
Keanu Reeves
and Bill and Ted
to Keanu Reeves
and John Wick
I would say
John Wick
was fairly
even keeled
I don't know
he was angry
if I were to get into
the psychology of
Keanu Reeves
but I
but he was an ass kicker
but he was an ass kicker
excellent
yes
and there was this concept
of
of
roid rage
right
this idea
you take a bunch of steroids
you get angry
you get mad
you get even
yes
is it true
um
I talked about this
with Justin Corre
he is a social psychologist
at Nipissing University
in Ontario
Canada
this is a hot topic
hot topic
in the US right now
Justin's watching the news
I like that
a scientist
with a finger on the pulse
yes
and actually
he's been studying
testosterone and aggression
for his whole career
and what he says is like
first of all
there's a lot of reason
to think testosterone
is tied to aggression
you know
think about
males
male animals
fighting for mates
like deer
you know
locking antlers
you can probably visualize that
right now
very classic example
and that is
testosterone
fueled behavior
we know that
because
if you
castrate
those deer
stags
I guess
they no longer do that
that's an experiment
that's been done
and you know
when you castrate
a male animal
you're basically
taking away
his testosterone
yes
but the story
of testosterone
is a lot more
complex than that
and that's
especially true
in people
and this is what
Justin studies
so let me tell you
how Justin studies
aggression
in the lab
great
he has people
play this game
with this
super
fun sounding
name
point subtraction
aggression paradigm
we don't tell them
it's called that
but we just tell them
it's a computer game
they're playing
point subtraction
aggression
paradigm
paradigm
great
in terms of like
how fun this game is
I would put it
somewhere between
like Pong
and that
test that they
make you do
at the eye doctor
to check if you have
glaucoma
okay
okay
so we're a far cry
from Zelda
yeah
how does it work
so you get a keypad
it has a few buttons
on it
and you've also got
a computer screen
you're told to hit
a button on your
keypad
a hundred times
when you hit it
a hundred times
you get one point
and Justin gives
people about
ten minutes
to do this
so at the end
of the ten minutes
you're gonna get paid
based on how many
points you got
so you get
fifty cents a point
so if you get
you know
twenty points
you're getting
ten bucks
right
you press it
a hundred times
you get fifty cents
got it
okay
so people
they want those
fifty cents
so here's where
the aggression part
comes in
Justin tells you
that you're competing
against somebody else
in another room
this is actually
not true
it's just like
the computer
being random
but you're told
that this person
you're competing against
can actually steal
your points
and thus
your money
and keep it
for themselves
and you get a flash
on the screen
when that happens
you can
take points away
from that
that person
but you don't
get to keep
their points
for yourself
so they can
steal money
from you
you can
take away
their money
from them
but you don't
get to keep
their money
so it's like
unfair
it's like a rigged game
it's just
vindictive
yes
exactly
exactly
okay
so the only
purpose of
stealing points
is to get
revenge
on the other
guy
and in fact
you're wasting
time hitting
a button
because you're
not getting
anything
you're not
getting any
financial
or any points
you're not
getting anything
any actual
reward from it
the reward
you're getting
is an intrinsic
reward of
you got back
at them
right
why would
somebody take
points from
the other
player if
they don't
get the
points added
to their
total
because
they're
pissed off
you know
it sounds
a little bit
silly but
scientists have
studied this a
number of
times and
found this is
a pretty good
indicator of
aggression
they even
found that
in people
who are
violent in
real life
when they
take this
test they
tend to
score higher
in terms of
all the
revenge point
hitting
Justin says
he can even
see this
when he
watches people
play this
game
they're like
sitting back
they're hitting
their buttons
like they're
cool right
hitting their
buttons
hitting their
buttons
and then
when they
get stolen
from them
like when
you see
them get
provoked
they like
lean forward
and they
start playing
harder
all right
so now
enter
testosterone
the testosterone
yes so
Justin has
done these
studies where
he gives
people a
dose of
testosterone
and sees
what does it
make them
play this
game more
aggressively
or placebo
so he'll
have some
people get
either a
testosterone
or a
placebo
and see
what happens
Wendy what
is your
prediction
you know I
guess based
on everything
we've heard
about testosterone
one might
expect that
if you get
a bump of
testosterone
it would
make you
press the
revenge button
more often
right
you would
think that
in reality
that's not
true for
everyone
so
�
what Justin
has found
in multiple
studies
is that
it does
seem to
make
some
people
more
aggressive
if
they've
got
certain
personality
traits
so he'll
give these
like
personality
tests
and finds
that for
people
who tend
to be
more
impulsive
and more
dominant
they're
more likely
to get
more aggressive
with this
testosterone
bump
here's how
he put
it
so if
you are
someone
who
is
likes to
have
power
and influence
over
others
someone
who
is
hyper
competitive
or someone
who's
yeah
I won't
even use
any examples
of people
that I
would think
are high
in dominance
but I
think you
get the
point
right
so
dominant
leaders
perhaps
right
right
I think
probably
all of
them
right
okay
you put
them in
this little
lab
give them
some
extra
testosterone
and it
will do
something
to make
them
press
that
revenge
button
more
often
but then
if people
had
other
personality
traits
I guess
lower
on
dominance
lower
on
aggression
more
generally
didn't
make a
difference
it did
not
make a
difference
this is
for
just
cis
men
I
couldn't
find
any
study
on
women
that
did
exactly
this
like
tried
to
take
into
account
personality
traits
but
there
are
studies
looking
at
aggression
and
testosterone
in
women
it
tends
to
be
more
true
for
men
that
testosterone
can
increase
aggression
for
certain
kinds
of
men
researchers
have also
looked at
this in
trans men
who take
testosterone
as gender
affirming
care
and in
some
of those
men
you see
an increase
in
aggression
and others
they didn't
feel that
at all
so again
we see
variation
in
the human
spirit
which I guess
isn't too
surprising
exactly
I mean
there was
this other
study
that
had guys
take tea
and
had them
take
journal
like
write
journal
entries
about
how
they
were
feeling
and
had
their
partners
or
significant
others
also
assess
if
they
change
if
their
mood
changed
and
found
that
like
it
didn't
happen
for
everybody
but
a couple
of guys
had
bad
reactions
like
one guy
had to
even
like
leave
the
study
because
they were
worried
about
him
and
there's
a study
in
cis
guys
yeah
yeah
so
this
idea
of
roid
rage
it's
not
a
for
everyone
you take
testosterone
you'll
get
mad
but
actually
it
doesn't
affect
everyone
in
that
way
and
the
science
tells
us
that
when
someone
asks
me
well
when
you
give
testosterone
it's
gonna
make
everyone
aggressive
and
I'm
like
well
wait
a
minute
not
everybody
not
everybody
up
next
let's
look at
testosterone
and
sex
drive
yes
will
it
make
you
a
total
horndog
I
Coming up.
We'll be right back.
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Welcome back.
Today we're talking about testosterone.
Our own senior producer, Rose Rimler, has promised to tell us whether taking a bit of tea can turn us into whore dogs.
I would have said horn dogs.
No, that's what I said.
I said horn dog.
I didn't say whore dog.
All right.
Either way, how does testosterone affect sex drive?
Okay, Wendy.
You need to hold your horn.
Or horn dogs.
Okay.
Just for a minute.
Okay, okay, right.
Before we dive into that, I just do want to say that, you know, one reason people are really concerned here is because of this idea that testosterone levels are going down in dudes.
There's never been a worse time in modern history to be a young man hormonally.
Testosterone levels are plummeting.
A 25-year-old guy has the same testosterone levels as his grandpa did at age 40.
Which is a problem.
It's a massive problem in men.
Yes, yes.
The so-called testosterone.
Testosterone crisis and whatnot.
So, for example, one study looked at testosterone levels of men between the ages of 15 and 39 in 1999 compared with men of that same age in 2015 and found that the modern dudes had about 25% less testosterone on average.
25% less testosterone, same age group.
Uh-huh.
Yeah, and other studies have shown, you know, different numbers, but similarly, like this decline.
Interesting.
So, this. What's causing it?
There's something in the water?
I mean, a lot of people point to, you know, endocrine-disrupting chemicals.
The microplastics.
Yeah, maybe stress, a more stressed-out society, a more sedentary society.
These have all been floated around.
But the point, I think, for our conversation today is that with this sort of decline in testosterone levels broadly, it could be pushing more men into the too-low category.
And by too-low, you. You mean when scientists study large groups of people and compare the health of a group of men, they find that there is a cut-off point where your testosterone is low and it starts to be associated with various health effects.
Is that right?
Right.
I mean, the normal healthy range of testosterone is pretty broad, actually.
But down below a certain threshold, you can get symptoms like low energy, feeling down, getting crappy sleep, gaining weight.
Brain fog and low libido.
So the question is, if that's you, should you take T?
Right.
Will it help?
So the best study we have on this comes from this group of studies called the T trials, led partly by our old friend, Shalinder Pasin.
We heard from him earlier in the show.
He and his colleagues in the 2000s, they enrolled this big group of older guys with low, clinically low testosterone, and they had them take either a testosterone gel or a placebo gel.
They would rub it on their backs every day for a year.
And they were tracking stuff like their sex life.
How do you find out about that?
You can't sit in the bedroom and take notes.
So he had these diaries.
So people jotted down for a whole week all types of sexual activity, you know, whether they masturbated or partnered activity or just whether they watched an X-rated video or Playboy magazine, etc.
So cute that he says X-rated and not porn.
Really dates the study.
I guess they got a videocassette.
Yeah, exactly.
Went to the video store with a sticky floor.
So what did he find?
All types of activities were recorded.
And those diaries showed clearly that all types of sexual activities improved.
So the guys in the testosterone arm at the end of the trial, about 20% of them reported that their libido was much better.
And that's compared with less than 10% in the placebo group.
Uh-huh.
Testosterone.
Testosterone did improve when they had low testosterone, clinically low.
And that, you know, really makes sense because we know that men who have severely low testosterone, like guys with Klinefelter syndrome, that's where you're born XXY instead of XY, they make very little testosterone.
One of the symptoms of that syndrome is a very low or non-existent sex drive.
We also know that trans men often report a boost in their sex drive when they start taking tea, at least at first.
It tends to. Settle down over time.
So it totally makes sense.
Yeah.
So I think the take-home is really if you have clinically low levels of testosterone, taking more to get you into that healthy range can boost your sex drive.
But if you are already in the healthy range, and like you mentioned, guys in the healthy range of testosterone, some have higher, some have lower, all in the healthy range.
And we know from. Study after study after study that when you ask those guys in the healthy range, how often do you think about sex, how often are you having sex, how often are you watching X-rated videos, and then you test their testosterone, having a little bit more or a little bit less actually isn't correlated with a higher sex drive.
That's right.
Yeah.
That's another really good clue that if you're in the normal testosterone range, it doesn't really matter.
And this brings us to our next question, which is, does testosterone help?
How does it help women with their sex drive?
So some of our best data on women and testosterone and sex drive come from East Germany, back before the collapse of the Soviet Union.
So back then, the state was actually giving their athletes steroids in order to win more Olympic medals.
And they were giving their female athletes especially high doses of something called terabinol and documenting the effects.
And those documents became available later on.
Right.
And they show that women getting these big doses of testosterone essentially got super horny.
In fact, some women reported that this was unbearable and asked to quit sports rather than keep taking it.
Wow.
I know.
And a more modern survey of female users of anabolic steroids that I found surveyed them and asked them about their sex drive.
And a lot of them said the same thing, that it really made the difference.
There's sex.
drive go up, but they didn't necessarily like it all that much. Now, both, I mean, I don't think
we want to call what happened in East Germany a study, but in both cases, there's no placebo
control. No. I mean, these are high doses though. Like we're talking about doses where you can grow
more body hair, your voice can deepen, you can get enlargement of the clitoris. The doses that
I think most of the influencers are talking about when they're like, you're a woman with low sex
drive, you should get on testosterone. They're much lower. And we do have a placebo control
trial to talk about when it comes to that. Okay. There's a drug company that tested this. They had
women who said that they had a distressingly low libido, randomized them to wear either a
testosterone patch or a placebo patch for a year. These were all post-menopausal women. The women
who wore the testosterone patch. reported about one more satisfying sexual experience per month.
Okay. One more sexually satisfying experience per month. I guess not kicking that out of bed.
I don't know. Sure. No miracles, but can help, but can help. Yeah. All right.
And just quickly, one final thing I want to look at, one final claim that I see everywhere
is this idea that taking testosterone will like put a lot more pep back in your step,
give you a lot more energy. Yes. Yes.
So this is another thing that Schallender and his
team looked at in the T-trials, people's energy. And other studies have looked at this as well.
And the result is always kind of like sad trombone, you know, like, "What, mom?"
Aww. Aww. In what way? Put some numbers behind our sad trombone?
For example, in the T-trials, the team measured what they called vitality
by giving guys a questionnaire that asked them stuff like, "How tired did they feel? How
functional were they day-to-day?" A max score on this questionnaire would be 108 points.
And the team decided before the study that a meaningful effect would be an improvement of
four points. Okay.
It didn't clear that hurdle. They saw a little bit of improvement, but the effect was really small.
And Schallender said that surprises him because when he treats patients with low T, and gives
them, you know, testosterone supplementation, he says they often tell him that they feel more
energetic after the T-trials. That's right. They often tell him that they feel more energetic after
they start therapy. And, you know, I've been the author on
many of these studies, and I'm always surprised by such a small effect.
Yeah, it's very underwhelming. Very underwhelming, isn't it?
Well, the placebo is a wonderful thing, right? Yeah, for all kinds of people, for all kinds of
things. You hear, like, it's basically going to cure everything that's wrong with you. And, you
know, we hear about it so much for menopause symptoms. This is something that came up a lot,
like your brain fog and, you know, your focus.
And all that. We don't actually have any research to back that up, but we do have our
studies that don't have control groups, and you really need one because of the placebo effect
from testosterone. Or they're funded by some clinic that's shilling testosterone.
This is what you're finding in the post-menopausal research space.
That's right.
So then what are the risks? What are the risks? Is it time to get to the risks? You've mentioned
your clitoris might enlarge. What else could happen?
So in people who have testicles, if you take testosterone, you know, give yourself a
big dose of testosterone, you know, chronically, you take it all the time, your brain is going to
sense that you have plenty of testosterone, and it'll stop making your own testosterone. It'll
stop the homegrown stuff. And that brings us to our biggest, most obvious risk, and that's
infertility. The reason that leads to infertility is that in order to make viable sperm, you need
testosterone to be coming from the testicles, right? Yeah.
Yeah. And that's not going to happen if you've turned off the tap that comes from your brain.
And people think testosterone equals masculinity, equals high sperm count. Actually,
exact opposite. The exact opposite. You're taking testosterone can lower your sperm count to the
point where you are infertile, right? Yes. And this whole thing about sperm
and about shutting off your own testosterone, it's not trivial and it's not necessarily
super short term. I talked about this with Richard Aukus. He is an endocrinologist and professor at
the University of Michigan. And this actually came up when we were talking about this idea
of supplementing soldiers with testosterone. But, you know, if you're taking testosterone,
you probably shouldn't be on the front lines fighting, right?
Why is that? Well, what if you get captured, right? Because remember, taking
testosterone, you're going to then become dependent on it. You're going to suppress your own production and then
you're going to have to take that for the rest of your life. So if you get captured and you don't
have access to your testosterone, then you're going to be even lower than you were before you got
treated. That's permanent? Well, I mean, it depends how long you use it. Yeah. Wait, it doesn't,
the moment you stop taking your testosterone supplements, your body forgets that it's got
to go up again? Well, it depends on how long you've been on the testosterone supplements. It depends on how much
you've been taking. But it can take a while to come back online and it can be permanently suppressed,
even when it does come back online, including your sperm counts. Wow. That's a huge, that's a huge risk.
It's a huge risk. And especially when I think about, like, teenagers taking this stuff, like, oh my god.
But yeah, I mean, also, you can actually go through withdrawal after stopping testosterone replacement therapy or stopping, you know,
steroids. You can get symptoms like headache, fatigue, restlessness, insomnia, feeling sad,
low sex drive, all this stuff that you're supposedly trying to avoid by taking tea can actually
end up getting worse after you stop the testosterone therapy.
And then what about other effects to your heart, to your, the rest of your body while
you're taking the testosterone? Yeah, so people talk about acne, that comes up, breast tenderness,
and also if you are someone who is capable of becoming pregnant, you get pregnant while you're
on testosterone, it could harm the fetus. It's another big thing to think about.
When it comes to stuff like your heart, your prostate, if you have one,
there has been a lot of concern that testosterone, taking it could, could be bad,
like give you heart attacks or prostate cancer. But we do have a study a drug company did a few
years ago that found no difference in heart attacks or prostate cancer for guys taking moderate doses
of testosterone compared with a placebo over four years, which is somewhat reassuring.
Okay. Yeah. But it might be a different story with much higher doses. So researchers have seen damage
to people's hearts and even brains after they've been juicing for a while. So there are certainly
downsides. Okay. So I think that can be really downplayed by people who promote this stuff.
For sure. And it doesn't help
that a lot of the information we get about taking testosterone is coming from people who
are selling it. A lot of experts have pointed out that this craze for testosterone really
took off around the year 2000, which was about the time that drug companies figured out how to
put it in a gel. And so you didn't have to just inject it so that this new product that would be
a lot more, you know, appealing to a lot more people. Right. Yeah. And so there's been a ton
of advertising since then to people and to doctors. Yes. And now the advertising
is coming through your favorite influencer and their favorite affiliate code.
Yeah. Right.
So there's this push by pharma companies, and I think it's dovetailing with this
other social change we're seeing. We're going to go back to the guys now. A lot of researchers
argue that we've actually seen a shift in what the ideal male body is supposed to look like.
Oh, for sure.
Over the last few decades. So they've done stuff like they've taken action figures of today and
compared them with action figures of the past, and they found that toy makers are actually making
them like buffer. Yeah. I mean, even if you look at He-Man, He-Man is probably looks like a twink
these days. Right? There's not even a vein in sight, you know?
Yeah. Yeah. Yeah. It's crazy.
That's crazy. It's crazy. They've also
compared centerfolds in Playgirl magazines over the years and found that the male models featured
there, they're getting more muscular. For sure. For sure. Online, you scroll,
and these huge guys don't look that huge anymore. That looks like that's what a normal
guy is supposed to be. Whereas in the past, you'd think, "Wow, that's a bodybuilder."
Yeah. And this is something that Shalinder really cares about and brought up and talked to me about
because he thinks what's going on here is we're getting this obsession,
and with this very narrow and unrealistic idea of what masculinity is.
What it means to be a man, a successful man, a good man.
I've seen some young men on social media talking about trying to get high T. They're
perfectly healthy, but they're like, "I want to be high T." Maybe they take T,
or maybe they're just trying to boost their T in other ways, but they really are fixated
on their testosterone. And sometimes I think like, "I feel like you need an older, wise, knowledgeable man
to give you some advice." I'm thinking you would be a great person, so if you could give some advice
to these guys, these young men.
young guys, what would you say to them? I would put my hands on them, hug them and tell them,
you have such a perfect, beautiful body. It is so perfect. It's beautiful in its perfection.
You don't need testosterone to be happy or healthy or have a sense of well-being, right?
And so I think these young men are struggling and they just need a hug and some reassurance.
That they are beautiful, their bodies are perfect and testosterone isn't going to make
them happier, more successful. That's science versus.
How many citations are in this week's episode, Rose Rimla?
This week we have 83 citations. And if people want to see them, where should they go?
They can click on the link to our transcript and they'll find that link in our show notes.
And if you have someone in your life that needs a hug, that needs to know how beautiful
their body is, share them this episode. They don't need testosterone, they need science.
Thanks, Rose. Thanks, Wendy.
Oh, and finally, if you are still thinking about the fact that children's toys have been getting
more and more muscly, not to mention, of course, these images that we're seeing online, just super,
super muscly men. Well, I had this amazing chat this week with the science educators behind ASAP
Science, Mitch Moffitt and Greg Brown. And we were talking about the fact that children's toys are
this growing mental health condition called bigorexia. And it really made me question my
own habits at the gym. I think it's a really fascinating conversation. It's out now. It's
on YouTube. We're going to put a link in the show notes. So please go check it out. And Mitch and
Greg have their own podcast. It's called Side Note. That is where I first heard about this
condition, bigorexia. So you should totally go check it out. This episode was produced by Rose
Edited by Blythe Terrell. Wendy Zuckerman, me, is the executive producer. Fact Checking by Marlo
Starling. Video Editing and Sound by Bobby Lord. Music Written by Bumi Hidaka, Peter Leonard,
Emma Munger and Bobby Lord. Thanks to the researchers we spoke to for this episode,
including Dr. Kathleen Casto, Dr. Carol Hoeven, Professor Ruth Wood, Dr. Stephanie Page,
Professor Sari Van Anders, Dr. Adam Stanaland and Professor Anthony Hackney. Thanks to Humdinger
Studios in Melbourne and Wolf Eyre.
Island Studios in New York City. Science Versus is a Spotify Studios original. Listen to us for
free on Spotify or wherever you get your podcasts. We're on YouTube, we're on TikTok, we're on
Instagram as well. Come and say hello. I'm Wendy Zuckerman. Back to you next time.
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Podcast Summary
Key Points:
Testosterone supplementation can increase muscle mass and strength, especially in men who lift weights, as shown in rigorous studies like the 1996 New England Journal of Medicine trial.
Testosterone does not universally increase aggression; its effect is linked to personality traits like dominance and impulsivity, and varies significantly between individuals and genders.
In men with clinically low testosterone, supplementation improves libido and sexual activity, with studies showing a 20% improvement compared to placebo.
For women, especially post-menopausal women, testosterone can enhance sexual satisfaction, with one study showing one more satisfying experience per month.
Testosterone does not significantly boost general energy or vitality in healthy individuals, and benefits are often overstated in popular culture.
Long-term use suppresses natural testosterone production and can lead to infertility, particularly in men, due to reduced sperm count.
Risks include cardiovascular concerns, withdrawal symptoms, and adverse effects like acne or breast tenderness, especially at high doses.
The widespread cultural obsession with testosterone is driven by marketing, social pressures, and unrealistic ideals of masculinity, not by scientific evidence.
Summary:
The narrative around testosterone has surged online, fueled by influencers, celebrities, and social media claims that supplementation boosts energy, libido, and masculinity. While science confirms that testosterone can help men with clinically low levels improve muscle strength and sexual function, it does not universally enhance energy, aggression, or overall well-being. Studies show that in healthy individuals with normal testosterone ranges, supplementation offers no significant benefits.
For women, especially post-menopausal women, testosterone can improve sexual satisfaction, but results are modest. Major risks include infertility due to suppression of natural hormone production and potential cardiovascular issues. The cultural obsession with testosterone often stems from marketing, unrealistic body ideals (like those in toys or media), and a broader societal shift toward narrow definitions of masculinity.
Experts emphasize that testosterone is not essential for health, happiness, or vitality—what matters most is self-acceptance and physical well-being. The science suggests young men do not need testosterone to succeed or feel good; instead, they benefit from reassurance, support, and a healthy relationship with their bodies. This episode calls for critical thinking over hype, urging listeners to separate scientific facts from influencer-driven myths.
FAQs
Yes, testosterone can enhance muscle strength and size. Studies show that men on testosterone who also engage in weight training see significant gains—such as 40% more weight in squats—compared to those on placebo. Even men not exercising gain muscle mass when taking testosterone.
Testosterone can increase aggression in some individuals, particularly those with dominant or impulsive personalities. However, it does not affect everyone, and the effect is not universal. Research shows that aggressive behavior is influenced by personality traits, not testosterone alone.
Yes, testosterone can improve libido, especially in men with clinically low levels. Clinical trials show that about 20% of men with low testosterone report much better sex drive after treatment, compared to less than 10% in the placebo group. For postmenopausal women, testosterone also increases sexual satisfaction.
Testosterone does not significantly improve overall energy or vitality. Studies show only small improvements in vitality scores, and the effect is minimal. Many users report feeling more energetic anecdotally, but this is not strongly supported by clinical data.
Yes, long-term use can suppress natural testosterone production and lead to infertility. It may also cause acne, breast tenderness, and, in rare cases, heart issues or prostate problems. Stopping treatment can lead to withdrawal symptoms like fatigue and low libido.
No. Men with normal testosterone levels do not benefit from supplementation. Studies show no link between testosterone levels and sex drive or energy in healthy individuals, indicating that it’s not necessary for general well-being.
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