Most Replayed Moment: Are You Really Gluten Intolerant? It Could Be This Instead!
19m 57s
Bloating and gas are commonly linked to constipation, not just frequency of bowel movements, but rather the quality and completeness of elimination. A significant portion of stool—up to 60%—comes from gut microbes that ferment dietary fibers, producing gas when digestion is slow or motility is impaired. Fructans in grains like wheat, barley, and rye are a major trigger for gas and bloating, not gluten itself, as shown by clinical studies where fructan-rich foods provoke symptoms while gluten does not. Fermentation in foods like sourdough reduces fructan content and improves tolerance. Environmental factors such as glyphosate in U.S. processed wheat may harm gut microbiota by disrupting beneficial bacteria, contributing to dysbiosis and digestive discomfort. Lifestyle, early-life microbiome development, and antibiotic use all play roles in gut health, with rising rates of inflammatory bowel diseases in industrialized nations. While genetics influence susceptibility, environmental exposures—especially gut disruptors like antibiotics—significantly increase risk. Ultimately, digestive issues are best understood as complex interactions between diet, microbiome health, motility, and immune function, requiring personalized, science-based approaches rather than blanket dietary restrictions.
[music] On this point about bloating discomfort, regular digestion, if I have one of those things, does that theoretically mean that something is not right? Everyone gets bored at once in a while, so I think it would be unfair to make it sound like you should never have any adverse symptoms at all, right? But if it's prolonged, if it's a chronic health issue, if you're the type of person who you wake up in the morning and you say, "I hope today is going to be a good day, I hope I don't have to deal with that specific issue," you have a problem. Like we already know, and then we have to work on that to address that issue. And how we go about that, I think, needs to be on some level personalized. But the tools that are at our disposal remain the same. So it's just a matter of, like, let's put it on the table. Here are your choices. You pick which ones are most applicable to you. Where are the opportunities for you? And I can't tell you that without knowing more about you. What about this issue of people getting gassy, like farting a lot, is that typically associated with one particular gut issue, or is that, again, could that be a plethora of issues? So it could be a plethora of issues. This is a common problem. If I have to, like, start with, what is my number one thing? It's constipation. For sure. 100%. There are so many people who are listening right now that are constipated and they don't even know it. Because they poop every day and they think that how often they poop is the definition. And that's not true. So constipation is what happens when you're not adequately emptying your bowels. And that could be a frequency problem. But it could also be that it's a partial poop. Oh, okay. Because I thought constipation was, if you just haven't been, you can't go to the toilet and nothing comes out. Look, don't get me wrong. If you don't poop for a week, I know you're constipated. I don't need to ask any more questions. If you go a week, but if it's, there are people who they poop every other day. That's their normal. They feel fine. They don't have any gut symptoms. They don't have a constipation problem. We're okay. Right? So frequency is not the feeling and end goal. It's part of the equation, right? But there's also people who they poop and I want to sort of paint the picture and forgive me. I feel very comfortable talking about poop. This is what I've done for a living. They go to the bathroom in the morning, they struggle. It's not satisfying. They had to work really hard to get a little nugget to come out. And then they feel like they still have to go. And maybe 45 minutes later, they poop again. Okay, that's not a new poop. You're doing partial poops. You're probably doing a 20 or 25% poop. So you could poop three, four times during the day. You might not still be fully emptying your bottles, right? So that's an example of a person who can actually be struggling with bloating and constipation and not think because they're like, Doc, I'm pooping three times a day. Where is the gas coming from? And that's it. Why do people. You eat something and then you fart a lot. What's going on? So gas travels with poop. You may. I don't mean you specifically, Steve, people listening may notice this that you wake up in the morning and you're farting like crazy. And that farting continues until you actually have your morning bowel movement. And then once you have your good, healthy morning bowel movement, you feel solid and you're not farting anymore, right? The gas travels with the poop. So and the reason why this happens is because, first of all, your poop is not just the leftover remains of your food. So your poop is predominantly your microbiome. 60% of the weight of your stool is microbial. Really? Yes. When you say microbial, you mean like the bacteria. The bacteria. 60% of it. Let me give you an example. If I took your drink and I added some soluble fiber, which is pre-botic into your drink. Yeah. There's no grit, there's no roughage. You don't even know it's there. And you're going to have a bigger, healthier bowel movement tomorrow as a result of what I just did. Why? Because I fed your microbes and they grow stronger and then they multiply. And because they multiplied, you have a bigger bowel movement, right? That's the way that that works. Now don't get me wrong. You eat, you know, a salad. You're going to end up with a bigger bowel movement as well. But a big part of that is the fiber within that salad that's feeding these microbes. They multiply. They grow and you have a big bowel movement. So if that was my, if that was my store, my poop, I'm holding a chocolate bar here. 60% of that would be the microbes. 60% of that would be the microbes, yes. So for that person, when the poop is in gridlock and it's not moving through, then those microbes are basically sitting there with unlimited time to ferment and produce gas. So anything they come in the contact with, they're just going to start working out. So if, and it's not just like a fiber thing, anything they come in the contact with, it could be protein, they will ferment it, they will produce gas. So this is a big part of the reason why constipation is so strongly associated with gas and bloating. When people eat dairy and things like that, and I think some people that have gluten, they often tend to get a little bit gassy, yeah. Is that constipation, gas and bloating is not just a constipation issue. I would argue that constipation is the number one cause of that particular issue. But there's many potential causes. Number one could be motility. That's constipation. What's motility? Motility is the way in which your intestines move. So if the intestines move too fast and out of rhythm, you get diarrhea. If the intestines slow down too much, sluggish, you get constipation. We want the intestines in a rhythm because when they're in a rhythm, just like your heart, that's when they perform their best. So in a rhythm, basically means predictable, consistent, daily bowel movements. That's ultimately where we would love to be, right? And that, in a way, taps into an entire circadian conversation that we can have later. This is a part of your circadian rhythm, is a fantastic morning bowel movement. Motility is just one of the causes of gas and bloating. The second is the microbiome. If you have a microbiome that's damaged and struggling, it's not going to be able to do its job the way it's supposed to. And part of its job is processing and breaking down fiber. Because the fiber in our diet, we don't have the enzymes to digest it. So it works its way through the intestines, comes in the contact with the microbes and the microbes. They have literally 60,000 enzymes that we don't have as humans. They go to work as teams. Fiber stops being fiber, produces short-chain fatty acids. This is the way that it's supposed to work. When your gut is not happy, they're weak, the microbes are weak. And you're asking them to do work. And they can't handle that. And you end up with sloppy digestion. And that's gas and bloating. The third thing can be your diet. So you just mentioned dairy, which contains lactose. Lactose can be easily fermented to produce gas. You mentioned gluten. Gluten itself is a protein, so can gluten technically be fermented? Yes, it could be technically fermented, but that's not really what's going on. What's happening is that gluten-containing foods, which are wheat, barley, and rye, also contain these carbohydrates called fructans. And fructans are actually really good for our microbes. They're pre-botic. But if you consume a very large amount of them and you're not used to eating these foods, they can cause gas and bloating. These days, when I was younger, if I had pasta, that's fine. If I have pasta these days, I'm going to feel it for the next two days. Really? Yeah, I don't know. I know I didn't even know what's going on. But then other people can eat pasta as much as they want it, it seems. At a curiosity, can you go to Italy and eat pasta and be okay or not? Same thing. I haven't really not really tried. But in Italy, I think when I have non-gluten bread or non-gluten pasta, I think I feel much better, but I'm well aware from speaking to people like yourself that such a small percentage of the population is actually due to intolerant, but we all kind of think we are to some degree. I think the numbers is like 20% of people think they are or something. So here in Los Angeles, it's probably 80% of people think that they're almost everyone's gluten free, which they don't need to be. And actually, it can cause problems. It can cause problems to be gluten free unless you know what adaptations to make. So when you ask that question about Italy, what are you getting at? There's a processing issue in the United States involving wheat, which is that they allow the wheat to be sprayed with glyphosate, which is roundup. It's a wheat killer, and they do that to basically dry it out as quickly as possible. So imagine for a moment that you're a farmer, and you have this field of wheat, you harvest it. Here are your choices, Steve. You can wait a couple of weeks and let it dry out naturally in the air and store it somewhere, or you can spray it with this chemical, and it will be dried by tomorrow, and then you can ship it up. Yeah. And the problem is that glyphosate is not on the label. You would never know whether it's sprayed or not sprayed unless you're buying organic. If you buy organic, then by definition, they're not allowed to spray it. You would never know if it's there.
been approved to exist in our food system under the assumption of safety, because what it does is it shuts down this thing called the Shikama pathway, and that kills weeds or it kills plants. And we have a workaround, and it has to do with basically amino acids. We have a workaround where we can basically create those amino acids as humans, but the plants can't, so the plants die we live. But there's a problem, which is that the microbes that live inside of our large intestine, they don't have the workaround. So that microscopic amount of glyphosate, you would say, "Well, us big humans, that's so small." Well, what do you think happens when it comes to the contact with them? We know that glyphosate disrupts the microbiome, that it depletes the beneficial bacteria, and the ones that tolerate it the best are the inflammatory ones. The bad bacteria. The bad bacteria. So you're shifting the balance, and this is a small thing, but I hear from people, Steve, that go to Italy, and they say, "I can't eat wheat in the United States." And then they go to Italy, and they're fine. And you think it's that glyphosate? Yeah, they don't do that, though. So if I try organic pasta tonight, and maybe that will be better. Yes. And then the alternative choice is, how do you do a bread? Are you okay? Not all bread. My generally, I stay away from bread. Okay. Do you ever eat sourdough? Yeah. Do you do okay with sourdough? Yeah. There we go. So here's the second part of this equation. Put the glyphosate. Put this aside for a moment. Let's talk about the fructans that we're talking about a moment ago. When you ferment your wheat, when you ferment your dough, you actually reduce the fructane content. What's fructane? So these are the long chain carbohydrates that exist in wheat, barley, and rye. So if it contains gluten, it also contains these fructans. Like gluten is not the only thing in wheat, right? And these fructans, again, they're good for you. They're good for your microbiome, but people who have a slightly damaged gut, they struggle to process and digest them. So this would explain why some people, they eat wheat-containing, gluten-containing foods, and they struggle. But they do okay with sourdough. Because if you ferment the bread, it reduces the fructane content, and actually then you can tolerate it. Oh, okay. So you think it might be the fructane in the bread that I have an issue with. And sourdough doesn't have fructane in it. Yeah. There was a study that was in gastronorology a few years ago. gastronorology is the top journal in my field, where basically they sent people home with a bunch of breakfast bars, all right, not chocolate, but nonetheless. They sent people home with a bunch of breakfast bars, three of them. One of them was a placebo bar, so they didn't add anything special. One of them contains a very large concentration of gluten. And then the third one contains the fructans. And the placebo is our standard bread, compared to that. When people ate the gluten-containing bar, and these were, by the way, people that they did not have celiac disease, they did have gluten problems, according to them, right? So like this is like the 20% of people that you mentioned a moment ago who think they might have a gluten problem. When they ate the gluten-containing bar, they actually had less symptoms than the placebo. So in other words, the gluten is not the problem. But when they ate the fructant containing bar, they were triggered. So basically what they said is that we have been taking this concept of gluten intolerance, and we've misnamed it. It's not a gluten intolerance. It's a fructant intolerance. These are people who are attending this struggle with these particular parts of that food. What foods contain fructane? So we barley and rye. There's many different types of fructanes, by the way. So you may not react to all of them. You may react to just some of them. But like garlic and onions are also classic. So you hear people who are like, "I can't eat garlic. I feel terrible," right? That can be a fructane issue. Tef, amrenth, sorghum, quinoa, these are whole grains that don't contain gluten, and they also don't contain fructanes. How long does it take to repair the gut when you have done damage to it? That's a very broad question intentionally, but generally for the average person who's done his sort of irritated gut, how long does it take to restore it for those microbes to grow back? It really depends. You have to start with, okay, what's your starting point, right? How deep is the damage? How bad is it? Because for the people who have ulcerative colitis or Crohn's disease, those are forms of inflammatory bowel disease. Those people have the deepest dysbiosis. Disbiosis is the word that we use for a damaged gut. Is it possible to reverse that? It's possible to put them into remission so deeply that they don't have a flair. Is that what the flair looks like on this little model that I have in front of me? Yes. So going back, for the people who are listening and not on YouTube, you can flip over to YouTube if you're interested, but what I'm showing here is the model of the large intestine. And the model includes a little area that it looks raw, ulcerated, it's bleeding. If you were to bump up against it, it's going to start to, you'll start to see blood coming out. So it's like a very vulnerable, sensitive area. Now these inflammatory bowel diseases, Steve, I have an interesting study on this topic. They are, to me, the classic gut inflammatory health condition. And what's happening is the immune system is attacking the microbiome. So technically, it's not actually autoimmune because autoimmune would be your attacking your own body. The immune system is not attacking your intestines. The immune system is attacking your microbiome and rejecting it. And because that's happening, your intestines are stuck in the middle. So this here is the immune system attacking the microbiome. It's attacking the microbiome, which is in the tube of the large intestine, and the immune system is trying to get at it and kill it. Why? And because it's decided that it's the enemy. So the immune system is confused because when we're born, we don't have much of a microbiome at birth. There are doses that we will get to not really having anything. And then during the first three years of life, you build your microbiome through your life experience. And by three years of age, you are basically fully adult sized in terms of your microbiome. During this time, your immune system is learning from and with those microbes. So there's this interplay between the two that is undeniable, where when the microbiome is healthy during childhood, during those first three years, it results in a healthier immune system. So what's going on here? The immune system is supposed to acknowledge your microbiome as being friendly, and it does not. It decides that your microbiome is the enemy. And so it's taking it out. So what do you think is for someone that has irritable bowel syndrome, all Crohn's disease? Or they have one of these big ulcers in their small or large intestine? Is it because of their lifestyle, typically? So lifestyle change or is it lots of things? What's the number one perpetrator? Okay. There's clearly a genetic component. Okay. So we have to be upfront about that. These are things that are not necessary within a person's control entirely. Because I mean, there's no evolutionary reason why this would happen. There's no evolutionary reason why you'd have severe gut digestion problems. No. There's no advantage to it, and these things that occur, they were quite rare years ago. In fact, in third world countries, today, there's not much inflammatory bowel disease. There's not a lot of Crohn's disease and all sort of colitis in third world countries. If you go to Africa, there's very little. And then what you see, though, is as countries industrialize, there's a take off. And they start ramping up. So within the United States, over the course of 40 years, from 1970 to 2010, all sort of colitis and Crohn's disease cases were increasing by up to 55%. And you can get that any age. You get that at any age, yeah. Even if I'm healthy right now, I could do a set of things that would give me this. Yes. In fact, if you take, so back to our conversation about antibiotics, if you take antibiotics, you're risk of developing an inflammatory bowel disease in the next year, just doubled. Oh gosh. If you disrupt the gut with antibiotics, which the antibiotics do, there's nothing that will basically like decimate the gut faster, reducing gut diversity, disrupting the gut barrier by 50% during, of course, antibiotics and activate in the immune system. It really speaks to that, like if you take antibiotics, these risks of inflammatory health conditions really start to go up. You see this in both adults and kids. What you just listened to was a most replayed moment from a previous episode. If you want to listen to that full episode, I've linked it down below. Check the description. Thank you.
Podcast Summary
Key Points:
Chronic bloating and gas are often linked to constipation, especially when bowel movements are incomplete or partial, not just infrequent.
Up to 60% of stool weight comes from gut microbes, which ferment dietary fibers and produce gas—leading to bloating when motility is slow or digestion is impaired.
Constipation arises from disrupted intestinal motility, not just frequency, and can manifest as difficult, incomplete, or infrequent bowel movements.
Gas and bloating are frequently caused by fructans (not gluten), especially in wheat, barley, and rye, which are poorly tolerated by a damaged microbiome.
Gluten itself is not the primary trigger; studies show fructan-rich foods cause symptoms in people who believe they have gluten sensitivity.
Glyphosate in U.S. processed wheat may harm gut microbiota by killing beneficial bacteria, contributing to gut imbalance and symptoms.
Fermenting grains like sourdough reduces fructan content, improving tolerance in those with fructan sensitivity.
Gut disorders like IBS and Crohn’s involve immune misidentification of microbes as threats, driven by early-life microbiome development and environmental factors such as antibiotics.
Summary:
Bloating and gas are commonly linked to constipation, not just frequency of bowel movements, but rather the quality and completeness of elimination. A significant portion of stool—up to 60%—comes from gut microbes that ferment dietary fibers, producing gas when digestion is slow or motility is impaired. Fructans in grains like wheat, barley, and rye are a major trigger for gas and bloating, not gluten itself, as shown by clinical studies where fructan-rich foods provoke symptoms while gluten does not.
Fermentation in foods like sourdough reduces fructan content and improves tolerance. S. processed wheat may harm gut microbiota by disrupting beneficial bacteria, contributing to dysbiosis and digestive discomfort.
Lifestyle, early-life microbiome development, and antibiotic use all play roles in gut health, with rising rates of inflammatory bowel diseases in industrialized nations. While genetics influence susceptibility, environmental exposures—especially gut disruptors like antibiotics—significantly increase risk. Ultimately, digestive issues are best understood as complex interactions between diet, microbiome health, motility, and immune function, requiring personalized, science-based approaches rather than blanket dietary restrictions.
FAQs
Yes, bloating and gas can be signs of digestive problems, especially if they are chronic or persistent. These symptoms are often linked to constipation, poor gut motility, or an imbalanced microbiome.
No, constipation isn't just about frequency. It can also involve incomplete bowel movements where only a small portion of stool is passed, leading to ongoing bloating and discomfort even if someone goes to the bathroom multiple times a day.
Gluten alone doesn't typically cause gas and bloating. The real issue is often fructans—carbohydrates found in wheat, barley, rye, garlic, and onions—that are fermented by gut bacteria and produce gas.
Foods containing fermentable carbohydrates like fructans or lactose are broken down by gut bacteria, which produce gas as a byproduct. This process is more pronounced when gut bacteria are weak or imbalanced.
Diet plays a major role—high fiber, prebiotic-rich foods, and fermented foods support healthy gut bacteria. Conversely, large amounts of fermentable carbs can cause gas and bloating, especially in individuals with a compromised microbiome.
Yes, glyphosate, a chemical used in some wheat farming, can disrupt the gut microbiome by killing beneficial bacteria, potentially leading to increased inflammation and digestive issues.
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