Flouride and IQ, Sardinemaxxing, At Home Cancer Cure, Hair Loss Fixes, and more... : 1451

I'm Dave Asprey. That's Dave's Bell DAI-V-E. And this is your 10-minute weekly upgrade on the biggest stories in biohacking, longevity, and the world of health. Let's go. Want to know which foods and supplements work best for your body? Viam takes the guesswork out of it. Their full body intelligence test reads your RNA. Not your DNA, so you see what's happening in your body right now. While standard labs measure around 100 markers, Viam's AI analyzes over 10,000 active pathways across your gut, oral, and cellular health. Then it translates that into personalized food and supplement recommendations built for your unique biology. They'll tell you what foods to eat and which ones to avoid. They even create custom supplements and oral care products based on your results. So what you're getting is what will work for your body, not someone else's. Your results update as your lifestyle changes, so your plan evolves with you. Check it out at Viam.com and use code 10DAV-E for 10% off. It's time to stop guessing and start knowing your body. Your hair is a sign of how healthy you are. So what actually works if you want to grow new hair? There are tons of products that sound good on paper, but they really don't do much in practice. I restore is different because it is powerful and it's targeted and it's light therapy. Your hair follicles directly absorb the light energy, which means blood flow increases, and that means dormant hair follicles can wake back up. The elite delivers that through 300 lasers and 200 LEDs directly to your scalp. And it takes an easy 12 minutes a day. And you can wear it while you're working while you're doing chores around the house. And the clinical results from it are amazing. Double blind study, 100% of participants grew more hair. In four months, their hair count increased an average of 43.2% and this thing really works. Plus, you get a 12 month money back guarantee. Try it for a year and see what happens and you'll like it. Spring savings is happening right now. So go to iristore.com, use code Dave and get an exclusive discount on the elite. That's iristore.com code Dave. This week, a self engineered cancer cure, a 70 year study that should embarrass half the country's legislators, and a missing fasting molecule hiding in plain sight. The information exists. The gap is between knowing and doing and that gap has a body count. So here's what happened. A virologist, someone who works with viruses professionally, understands the biology at a deep level, was diagnosed with triple negative breast cancer, the most aggressive subtype, with survival rates that are super grim. Rather than wait years for a clinical trial that might never enroll her, she engineered two on-calytic viruses. That's viruses that preferentially infect and kill cancer cells and injected them directly into her tumor herself. Measel's virus first, then the secular stomatitis virus, seven doses, then three more. And four years later, she has no detectable cancer. Here's what I think about this. I've been saying for a long time that the regulatory system around experimental medicine is costing lives, not saving them. Uncalytic virotherapy is not fringe. The FDA has already approved a version of it for melanoma, and Dana Farber just published results showing it extends survival in brain cancer. What this woman did was apply established immunological principles to her own terminal diagnosis on her own timeline. Was it risky? Of course it was, but the alternative, a 28% five-year survival rate while waiting for phase three trials, is also risky, and it's the kind of risk nobody talks about. The risk of doing nothing. The risk of trusting a system that moves slower than your tumor grows. I'm not telling anyone to go inject viruses at home. But I am telling you that patient autonomy in end-stage disease is a conversation where decades overdue for having. The upgrade here is awareness. Uncalytic immunotherapy is coming. Fast. Ask your oncologist about telemojean-lehair-perreptvic and what oncologic trials are currently enrolling near you. This is not alternative medicine. It's the leading edge of mainstream oncology just ahead of the paperwork. A landmark study, and I mean that. This one held up across yeast, flies, worms, and mice, figured out that fasting only extends lifespan because it raises a molecule called spermedine. Fun name, serious science. When researchers genetically blocked spermedine production and then put animals through the same caloric restriction protocol, zero lifespan extension, zero cardio protection, nothing. The fasting benefits completely disappeared. They also showed the reverse. Gives spermedine to animals that can't make it themselves, and you get the longevity benefits back even without fasting. This is one of those studies that makes me go back and look at my own stack. I've been fasting for a long time. I was one of the early advocates for intermittent fasting long before it was trendy, and I've always known the benefits go beyond just calorie restriction. Now we know part of the mechanism. Spirmedine triggers autophagy, your cellular recycling system. Through a specific pathway that requires this polyamine to be present. If your spermedine levels are low, you're stressing yourselves without triggering the repair response. You're getting the hard part of fasting without the payoff. Most people have no idea their spermedine is low. Most doctors have never mentioned it. I've been supplementing it for a while now, and this study makes me feel even better about that call. So here's your upgrade. Add wheat germ to your eating window. It's the highest food source of spermedine by a wide margin. Or grab a spermedine supplement, which runs about 15 to 30 bucks a month. If you fast and you're not doing this, you might be leaving the most important benefit on the table. Monoxidil has been one of the only popular topical hair loss option for three decades. And here's the thing about monoxidil that nobody says out loud. It was an accident. It was a blood pressure drug. Someone noticed it caused hair growth as a side effect, and we've been using that accidental observation ever since. It works through vasodilation, more blood flow to the scalp, which also means systemic cardiovascular effects in some people. Now there's a new class of topical peptides that mimic sonic hedgehog signaling, which is the actual embryonic pathway that builds hair follicles from scratch. Clinical data shows 65% regrowth versus 40% with monoxidil, faster onset and zero cardiovascular side effects, because the molecules are too large to cross into systemic circulation. I find this one satisfying on a philosophical level. This is what first principles biology looks like applied to medicine. Instead of using an accidental side effect of a blood pressure drug, you're directly activating the signaling pathway that tells your scalp to grow hair. It's like the difference between fixing a leaky roof by increasing your bucket inventory versus actually patching the roof. The mechanism matters. Availability is still limited. Early trials and off-label access for now, with broader approval expected later this year. But if hair loss is something you're managing, this is worth tracking closely. The better version of the tool is almost here. So here's what I want you to do. Look into SHH memetic peptides, specifically strand therapeutics if you want to track the company closest to FDA submission. And if you're currently on monoxidil and experiencing cardiovascular side effects, know that there's a mechanistically superior alternative in the pipeline. TikTok discovered that canned sardines are basically a multivitamin that costs a $1.39. A Northeastern University researcher confirmed the numbers. 1.3.75 ounce can delivers 370% of your daily B12, 96% of your selenium, 24% of your vitamin D, and almost a gram of omega-3 fatty acids. That's EPA and DHA combined, which matches or beats most fish oil supplements you're paying $40 a month for. Look, I've been eating sardines for years, so I'm not going to pretend this is a revelation to me personally. But I'll say this, the cost to nutrient density ratio on sardines is genuinely hard to beat. And I think a lot of biohackers get caught chasing expensive supplements when the fundamentals are sitting on a shelf at Whole Foods for under two bucks. Selenium is one I care a lot about. It's critical for thyroid function and glutathione production, which is your primary antioxidant defense. Most Americans are subtly deficient and don't know it. B12 methylation is foundational for basically every repair process in your body. These aren't minor nutrients, and sardines deliver them in a bioavailable Whole Foods form with no manufacturing variability or absorption concerns. The upgrade is simple. Eat a can of sardines two or three times a week. Packed in olive oil, not soybean oil. Check the label. That single habit covers more microtritional ground than most supplement stacks I see people running. Modern life keeps your nervous system in overdrive. Most solutions try to change your brain chemistry, but your body also runs on electrical signals and rhythms. Your brain uses electrical weight. your heart beats in patterns, and your nervous system sends signals through tiny pulses. Light and sound are also forms of energy your body can sense. Scientists have studied them for decades because certain wavelengths and frequencies influence how cells and nerves respond. That's why I use the One Device. It combines light and sound in a wearable. It sends gentle signals your body can respond to while you work, meditate, or wind down. Most wearables just track stress. The One Device supports your nervous system directly, without any Bluetooth or EMFs. People who wear it report sleeping more deeply and feeling calmer, more focused, energized, and grounded. It's wearable frequency support you can use all day long. Learn more at theonedevice.com/dave. Researchers just published what is the most rigorous fluoride study ever conducted in the United States. 70 years of data, over 10,000 people tracked from high school through age 80. They cross-referenced actual municipal fluoridation records, with IQ scores taken at multiple points across participants' lifespans, controlled for income, education, lead exposure, nutrition, the works. The result? Zero statistically significant association between community water fluoridation at the US recommended level of 0.7 mg/l, and lower IQ or accelerated cognitive decline at any age. Here's where I land on this, and I want to be precise because this topic gets sloppy fast. The studies that showed IQ harm from fluoride, the ones that drove policy reversals in 17 states, were mostly conducted in regions of China and India, where natural fluoride levels ran two to ten times higher than what comes out of an American tap. Applying those findings to US community water was always a data transfer problem, not a scientific finding. This was Conson Study, closes that gap. At 0.7 mg/l, the neurotoxicity narrative is not supported. Now, I've been filtering my water for decades, and I'm not stopping. I filter for a lot of things beyond fluoride, and I think controlling your water quality is just smart. I also think thyroid effects and skeletal effects at higher doses are worth watching. But if your primary concern about fluoride is your IQ or your kids IQ, this study is telling you that at community levels, that specific fear is not backed by the data. That's not a pro-fluoride position. That's a pro-evidence position, and I think that distinction matters. Here's what to do. Get a quality water filter, regardless. Not out of fear, but because controlling input quality is foundational. But stop letting fluoride anxiety be the driver if you're in a standard municipal system. Save your worry budget for things with actual evidence behind them. Here's the thing nobody says about biohacking. The biggest gains almost never come from the newest, most expensive intervention. They come from removing the wrong assumption. This week, it was the assumption that fasting alone is enough, that monoxidil is your only option that fluoride fear is grounded in American data, that you need a clinical trial to save your own life. Every single story this week was less about a discovery and more about a correction. And that's actually the skill, not collecting more information, but identifying which belief you're holding that's costing you. One bad assumption held long enough becomes a protocol, becomes a habit, becomes a decade of sub-optimal biology. Get good at finding those. That's the real upgrade. Alright guys, that is your weekly biohacking roundup. Join me again next Friday for another rundown of the biggest health stories in the news. Enjoy your weekend. The human upgrade, formable approval of radio, was created and is hosted by Dave Asprey. The information contained in this podcast is provided for informational purposes only and is not intended for the purposes of diagnosing, treating, curing or preventing any disease. Before using any products referenced on the podcast, consult with your healthcare provider, carefully read all labels and heed all directions and cautions that accompany the products. Information found or received through the podcast should not be used in place of a consultation or advice from a healthcare provider. If you suspect you have a medical problem or should you have any healthcare questions, please promptly call or see your healthcare provider. This podcast, including Dave Asprey and the producers, disclaim responsibility for any possible adverse effects from the use of information contained herein. Opinions of guests are their own and this podcast is not endorsed or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guest qualifications or credibility. This podcast may contain paid endorsements and advertisements for products or services. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. This podcast is owned by Bulletproof Media.