Biohacking for Real Life: Sleep, Omegas & Strength

When we talk about biohacking, you want to be able to actually measure something that will have a meaningful impact on you. Because there are tons of people out there who say, "Do this, it's a great biohack. What do you mean? What will it change?" What is the outcome that it's changing? All right, welcome back to her Health Her Way. I'm Jen Krubekowicz and today we have a very special episode. We have Dr. Russell Azgethorpe. We call him Dr. O because of the way his name is a little bit difficult to say. So if I refer to him today, it will be Dr. O. But we are diving into actual clinical data that he's going to share with us on aging backwards. It's phenomenal. He and I sat down a few weeks ago and he shared some of this data with me and it blew my mind about aging backwards. And I'm all about that and always for longevity, for regaining some youthfulness and just being able to age a lot more gracefully and to be strong for my grand babies. And for our children and so that we can be healthy until the time passes that we pass on to the next life. Yes, Dr. O is the chief medical officer at Dotera. He has an extensive background. Has done so many things. He's been a director, a medical director, a pediatric infectious disease specialist, pediatric. You worked at hospitals. You've done so many things. I mean, your bio is extensive. We'll drop it in the show notes. But your research really is phenomenal to me. Everyone knows this show is all about natural living and essential oils. And so I love learning about the products that I know work, but I don't always know why they work. And so this research is really exciting for longevity and biohacking and those are the buzzwords kind of now too. So we're going to go into three biohacks that actually work and show the clinical data. So Dr. O, the one piece of data that you shared with me a few weeks ago when we were talking to our 90 day reset group, which was a private group. So that's why I was like, we have to have you on the podcast to share this was about people's brains getting seven years younger, which is incredible. So can we start there? It seems almost impossible to think that your brain can go back in age and you can be a little bit sharper. So walk us through the study that was looked at the serenity study. The serenity, the sleep system, we have a doctora. It contains three products, a dietary supplement, which is a supplement of pill that you take at night, a force move, a topical application, serenity, this step, and an aroma base or the essential oil, which is proprietary blend that contains a backbone of lavender essential oil. So what we did was we looked at a relatively large group of people and we did two weeks of aroma and then added to the aroma based application two weeks of the stick and then added to the stick two weeks of the supplement. And we then looked at outcomes at each juncture of the study and comparing beginning to end with how people slap how much sleep they got in what type of sleep they receive what stages of sleep a much ram how much stage three stage two, et cetera. And then we also looked at epigenetic information. So epigenetics is a term that I think is really coming into its own now in the biohacken community as we understand. How powerful our genes can be if we influence their expression actually change the way that our genes are expressed based on what we do. So, for example, exercise weight loss will take years, every year, chronologic age will make you younger. Other things that you can do that will do the same thing better sleep. Does that for us as well. And for you if epigenetic we use DNA methylation or method of looking at epigenetic expression looked at what are called biological clocks or epigenetic clocks. Our brain age in this study when we compared time zero to the end of the study, we showed a seven year decrease in the brain age as measured by the epigenetic expression of the brains before starting the program and after being in the program, which is really powerful thing. It was a six week study. Oh, powerful. Okay. Seven years of brain age off of the individual study, which was about statistically significant. And of course, clinically. Yes, yes. So the way that you did it, you said was two weeks of aroma based two weeks, then you just layered the next one on, which was the serenity stick and then thirdly, the serenity soft gels. The reason we did that is we wanted to evaluate each application on its own, okay, as well as the whole system to get. So we recommend using the whole system together because the finding that I'm describing, it was found after all three parts of the system were used together. Okay, so most powerful results occurred at those last two weeks. Absolutely. And that biological clock, the brain age clock, that was one of six different box that were statistically significantly factored by improving our sleep with the serenity system. It was a really remarkable. Wow. So when you measure brain age, it was, it was based on that methylation you were talking about, right? Okay, so we can actually look at the pattern of gene expression. Okay. Certain subset of genes that are associated with the brain age, the image at a clock of your brain. And the pattern, meaning how much a certain gene is on versus off, tell us your brain age. And we can measure that quite reliably. This is a, to relatively new field of science, but it's really well developed at this point. And it's a very trustworthy out. Yeah, absolutely. So, obviously, I think I know the answer to this question, but I want to ask anyhow, so is that temporary while they're using the products or could it be permanent? Their body get used to it. No, we don't know, because the study itself, of course, you know, at the terror, we'd love it to be permanent. I'd love to be able to tell you that it's permanent. The study itself was a six week study. But tell me, well, if I use it for 12 weeks, will I get 14 years younger? Right. We don't know that either. Don't be me asking that question. That is some point in that six week period or if we had gone out 12 weeks, there's going to be a plateau. Like our point in my brain back into a toddler based version of me, but we actually don't know how long that effect would last. But I will say that sleep, what we know about sleep, would indicate to me that the effects that we measure on the epigenetic age or the brain age that we are at, really dependent on the quality of our sleep, what the system is doing is improving the quality of our sleep, and as it improves the quality of our sleep, our brain age gets better. And there's some biological reasoning we could get into if you wanted to learn about that or if you wanted me to discuss that. If we went back to our old pattern, if we went back to average sleep or less than average sleep, I think our brain age would revert right along with us. Sure. I think that they are linked and that you need to be taking care of your sleep like you would any other part of your health if you want to maintain that. Yeah, there's been a lot of biohacking on sleeping. I feel like over the past few years of reducing the light in your eyes and making sure you get sunlight right away with no contacts or glasses in the morning and just all of the things. And so it makes sense that it would a level of certain wavelengths of light. Yeah, it's crazy. Stronger in improving our sleep and our waking state than other wavelengths. It's really quite remarkable how much we're learning. It is. It is. So it only makes sense that we would we would probably continue on with a protocol like you said to care for our sleep hygiene. What was the exact protocol that you felt like gave the results? I'm sure you guys kind of clinically measured it. Yeah, so we we had a diffuser at the bedside that diffused 30 minutes before the the individual was planning on going to sleep. Diffused all night long. Okay, so consistent all through the night goes. There are lots of variations that could could have been tried. That's the one we used in the study. The second thing we did is that we used the topical sleep stick on our forearms and upper chest. In two strokes on each arm and then on the upper chest and then we took the serenity soft gel at night. Did they do one or two? I take two at night. So I'm curious. Do you remember if it was one or two? One, I think it was one that we use. Okay. I used to take one. Then I was like, I think I need two. I'm I'm 47. So I think this leap one, not all not all months, but in certain times of the month, I'm like, I need two. Everybody's body is going to be slightly different. Okay. We tested in the study. Nice. Nice. Well, it clearly had fantastic results. So this is all serenity products. We're not talking about lavender diffusing. We're talking about serenity oil. That was what was used in the study. Can people overdo it with these sleep supplements? What are your thoughts on that? Yeah, I think that you certainly can. We always love to talk about our super users. We think one was tested for or better. And I'm not sure that that's the case, especially with certain essential oil products that are extremely powerful. And I've potential side effects if we were to use too much. So too much of a good thing is too much of a good thing. And the problems we experience as we do anything are mostly experienced through the lens of dose is your exposure risk. So the higher the dose for more your risk. So as we as we start looking at sleep supplementation, one of the ways that I would recommend that you look at it, look at it is through the lens of melatonin. Okay. For the longest time we talked about melatonin, the medical community as a sleep aid. And we were giving people this idea that well more is better, more is better, more is better. We've learned in just the last several years that too much melatonin actually has the opposite effect on sleep. Disruptor sleep and cause that it's a much smaller dose of melatonin that's most effective at helping people sleep or at least the vast majority of people sleep. Right. Or exceptions to that rule based on individual situation. But long story short guess, too much of a sleep supplement can be a problem as is bit proven by melatonin. We don't know that a threshold or that what we would call exposure limit for a lavender based system like serenity. But I would still think that the results that we've obtained using the product in the way that I described earlier. Are super sufficient for the vast majority of people and I wouldn't go about that. Yeah. Yeah. Absolutely. No, I agree. And just to be clear and to clarify serenity capsules that we are ingesting internally do not have actually melatonin, they have the tart cherry that sort of acts like our natural melatonin. Is that correct? Maybe you could expand on that. I didn't really specify I wanted you to talk on that. But if you if you want to, that would be fantastic. Not cherry and melatonin have very similar effects, but are not the same thing. And we use tart cherry and a dose that's been therapeutically tested to achieve the same sort of results that a similar dose of melatonin which so we combine that with the serenity and lavender based systems which have been shown to also improve relaxation and call. So yeah, it's been really helpful without any of those concerns that melatonin has. And then there's also a little fanning. So am I saying that right? El fanning in there. Tell us a little bit about that. I actually need to learn a little bit more about that there. There's actually these drinks that I happen to find and they were they're called moment and it's a non-alcoholic beverage. But it has L-thienine and magnesium in there and it's like a relaxing like beverage instead of an alcohol based. So I was like, hmm, but it does make me very sleepy. And so I was like, I'm not familiar with that with that drink, but L-thienine is a well-tested, described molecule that aids in relaxation. Okay. Brain. It's critical for many aspects of development as well as neuronal cell help. So I think that we were very wise. They could. Right. And putting that into the serenity system. That makes sense, especially with the brain aging backwards and especially seeing that. Yeah. Well, we've been able to clinically measure it. Yeah. It's hard. I would love to, as a scientist, be able to do a clinical file on each endudiant. And then I'll individually gather and ship us up. It's in the effect. So which ingredient is having the most effect within serenity on our brain age? I actually don't know because we have not done that granular level of a study. We've built it each ingredient is powerful, but it's looked at prior to us doing this research epigenetics on serenity. Nobody has looked at the epigenetics of a dietary supplement with these ingredients. Nobody. This is the first time this data has been available. And it's pretty, pretty neat. And there has been quite a bit of study not on, of course, that supplement, but lavender, right? Like there's, there's a great deal of like, hug meds stuff that you can find on lavender essential oil and taking it. It's a thousand of articles and stuff. Yeah. But this is the first epigenetic stuff on epigenetics product. Okay. It is then. Yeah. There's not been any, at least that we were able to get you're aware of by literature search. Very powerful study and we know that lavender is powerful. We, lavender has been used for eons in so many different ways to help. Sleep has always been one that lavender has been linked with. And this study now proves mechanism of how it's doing it. It's altering our genetic expression of neurons in our brain and helping our brain sleep. Remember, Jen, that it's during our deep restful sleep, stage of sleep, that our brains actually recycle the metabolic byproducts, the trash from the day-to-day living and the stress of that we experience every day when we are awake. Without sleep, we actually cannot survive. We will die without adequate sleep. Yes. Sleep deprivation, the brain cannot function without a period of rest. And the reason it can't function is because it during sleep is how the brain regenerates. How the brain actually takes out the trash and the biometabolic byproducts of everyday living get written from the brain through our central cerebral spinal fluid. Remember you saying that? The spinal fluid is created in our brain, it then filters out and out through our spine and into our body and out through our urine and waste mechanisms. If you get better sleep and more deep sleep, then your brain regenerates better. And I believe that's mechanistically what we're seeing. The metabolic beta is a brain that gets better, restorative sleep. And when the brain gets better, restorative sleep, it functions better. And the reason it's functioning better is because it's expressing the genes within those cells are being expressed in a younger manner. It's so fascinating, it's so true because I wear an aura ring so I can track my sleep data. And there was, you wear the garment, those are fantastic too. But there was a night and it said I only had 32 minutes of deep sleep and when I woke up in the morning, I was so foggy and I was like, I just felt like I never got into a deep sleep. And then of course my sleep score was pretty poor that night. But then then it was almost, I think it was like an hour and 45 minutes of deep sleep on another night. And I felt fantastic the next day, I had clarity of mind and I was like, it's so true exactly what you're saying. And it makes sense and it was funny when that happened. I was like, I remember Dr. O's saying I had to recycle something in deep sleep. I couldn't remember all the details. But we all know this to be true because we all asked ourselves, you're always asked every morning, how did you see? We've been asking that question for thousands since we were little. Yeah, really as a species, we've been asking that question for thousands of years because we know the difference, a good night's sleep makes. Clearly when we wake up in the morning, whether we slept or not, and we don't need one of these. That's the truth because I didn't act the sleep data until I was like, I don't feel good. I feel allowed here. Yeah. Or you wake up refreshed and you're ready for the day and we all know that. If you wake up that way more, right. Carry your sleep. Like make it a priority. And serenity is a great way to do that. No, I think it's fantastic. I always say your better day starts with your night of sleep. Like that's actually when your better day starts. So no, this is correct. You said that earlier when you said, what are the, what are these three bio hacks we can do? Better sleep is absolutely proven to have a multitude, a multiplier effect on our whole body, not just our brain, but our whole body. Yes. No, I 100% agree. And I think this is such an easy symptom to our symptom and easy, an easy system to implement into anyone's lives. I know my daughter-in-law, she's, she uses it on my grandson. She doesn't use the serenity soft gels, of course, but she uses the stick. I thought it was interesting though. I always use it on my feet more so than like my chest or across my arm. So I'm going to add that. So that's good to know. We did it on skin that was uniform more often. Some people's skin on their feet is very thick. They keep it thin. And so it was, it was something that was made it more difficult for us to rely on a certain level of your forms and on your upper chest is quite uniform. And so we, we, we did that to make sure that we were comparing apples consistent. Oh, that makes sense. Yeah, that makes total sense. Now I love it. So let's switch gears a little bit to the Omega 3 game changer. This one really seriously blew my mind. I know I said they all blew my mind, but the gene expression on this was crazy. So when we were on our other call, you mentioned, of course, Omega's have been researched for many, many years, but there are 978 genes affected versus 33 with just regular fish oil using our wild orange oil in our capsules with our fish oil. So that's like 30 times more powerful. It's crazy. So what's happening with Doutera's Eomega fish oil with wild orange infused in it versus just a regular fish oil supplement? That's a great question. And I've been asking myself that question. And tell you what I think the answer is. And I'm a scientific perspective. I can't tell you that I know what the answer is. But there's certain things that are quite easy to say. And then we'll get into a little bit of the well and not quite sure. The most easy way to approach the answer to your question is to say, we were comparing fish oil alone, a high quality, very good fish oil, the same fish oil that we used in Eomega+. So we were comparing apples to apples in that respect, same quality fish oil. The only difference is that in Eomega+, we added a therapeutic dose of wild orange oil. And that therapeutic dose of wild orange oil was chosen based on the extensive data that exists on the compound limony, limony makes up about 97% of wild orange oil. And many citrus boils contain lots of limony. Great fruit is 99%. Oh, wow. So why not choose grapefruit? Well, because we wanted to use wild orange oil for other reasons. That was not me. I wanted limony. I didn't care how they gave it. So I left the marketing and products. Yeah. Well, wild orange tastes really good. I literally choose to chew those capsules. Right. So we chose there are thousands and thousands of articles published on limony as a compound that has been looked at in clinical studies. And so we had a very good idea of what we call the therapeutic window, meaning that you don't want to go above this level because side effects because it's a powerful molecule and you don't want to go below this level, go below this, you don't see any effect. So we picked a level that was right here, right, a couple of that therapeutic window. And by doing so, we knew we were going to see very powerful effects because of the thousands of articles that have been published on limony and passed. Right. So when we combined limony with fish oil, this high quality fish oil, we saw that 978 genes were statistically significantly altered, meaning that they were increased over five full or decreased. Over five fold over their baseline expression. So what did fish oil alone, like you said earlier, was only 33 genes that were statistically significantly altered in the same manner. So the difference is limony. Now if you were to be really savvy and say, you know, Dr, would you have expected, you know, 930 some genes more to be affected by limony? My answer is no, I would not have expected that. But that's the beauty of science and nobody's done an epigenetic study on limony. This is the first, really what this study was, everybody uses it uses it at doterra as a eomega study. It was actually a study looking at the comparison of limony. What does limony do in the body? Because we had a control group with fish oil and fish oil limony in here and the only thing different was limony. And the wild orange was, we did a wild orange oil study and we subtracted out those 33 and now we have 940 genes that are the genes that are affected by limony. And nobody, that that would be the case. I wouldn't have expected that through case. But that's what wild, that's what wild orange oil does in the body is it statistically significantly altered the expression of 940 gene. So do you feel like it's the synergistic effect of the eomegas and the wild orange? Is it specifically just wild orange? It's a great question. I know. It's at least additive. Yeah. So additive means that one plus one equals two synergistic is one plus one equals four. So in this sense, it's at least additive and the way that I know that or the reason I think that is because when we lifted our healthy people, we only tested the supplement. Like the serenity system was only right and healthy people. We lifted healthy people with our eomegas study and we saw that with fish oil alone blood pressure, the die stock blood pressure came down, which is what you would have expected based on other fish oils. But it did not reach statistical significance. That the decrease that we measured could have been done could have been due to chance. Okay. But when we looked at fish oil plus wild orange oil, blood pressure, the die saw blood pressure came down, but it came down more, came down statistically significantly, meaning that it was highly unlikely to be due to chance that we're measuring this difference. Wow. And so for that reason, where we, and we saw that as well with resting heart rate, we saw this thing, thing with resting heart rate, resting heart rate came down with fish oil, but it came down more with fish oil plus wild orange oil. And here we did not reach statistical significance and with the omega we did. And because of that, I believe that it is at least additive what we receive. And cappogenetics sheds light on how genetically these things are controlled. So when we see the heart rate drop, well, how does your heart rate drop? It's under genetic control. Genetics of your body, your DNA doesn't change, but your expression of that DNA changes. And then it changes your biology. That's amazing. That's amazing. So very cardio protective, you talked about that in our other chat that we had because you explained diastolic blood pressure and how I think you said the pressure, you can explain it pressure against the heart. So it has to do less of that is one, right? And then of course, resting heart rate is giving your heart, if you can drop that, I'm always trying to get my resting heart rate a little bit lower at night. And I have gotten it down to 61, which I still think is still high because I'm so, you don't think it's that's a good number. Okay, good. I feel a little better. And my doctor was it for the day. I got, I got an approval. I always feel like it should be in the high 50s or something, but I'm so active. And I'm like, why won't my mind go under 60 but you don't, you don't need to be any lower. Okay, good. So the most important thing I would say to help kind of tell you about the cardio protective benefits of Eomega plus or or visual plus our wild orange oil is to explain what these two clinical measures did. So in healthy people, we saw that our blood pressure dropped by six points and our resting heart rate dropped by four points. So when I say that it's cardio protective, what I'm saying is that the heart does not have to work as hard when it's pushing blood out of the heart. You have to push that blood forward all the way down to your big toe, right? Get that blood all the way there. It's pushing against a pressure wall. And that pressure wall is now six points lower when you're on to soil plus wild orange. So your heart has to work harder to do, sorry, work less hard to get what where it needs to go. So over a lifetime of heartbeats, your heart is yes, right. And your heart has to do less work. It will wear out smokes. Same thing, number of heartbeats in a day, if your heart rate is beating four times less a minute, if you add that up over a lifetime of minutes, that's huge. Notably high number of heartbeats that your heart does not have to do any work to let you live. Exactly. Because there are tons of people out there who say, "Do this, it's a great biohack." Right. What do you mean? What will it change? What is the outcome that it's changing? Right. We can see that our sleep improves. We can see that our brain age improves. We can measure those outcomes. With Eomega Plus, we can measure the outcomes of the cardio protective benefit over a lifetime of using official oil product in saving this many heartbeats and saving this much work that your heart has to work to push that blood forward. Does that make sense? Oh, absolutely. I love it. I love it. Even talking about sleep and decreasing brain age, there's so many benefits that go along with that biohacking, the cognitive benefits of just having a better quality of life and remembering. There's just so much that it goes so deep that it really does improve that biohack is huge. Both of those are huge. Taking those capsules are actually an enjoyable part of my day. People who are listeners who maybe are not familiar with our Eomega Plus product, it's a fairly large capsule filled with our omegas and our wild arms and we bite them. So I remember when somebody recommended biting them. I was like, "Oh, that's nasty. I used to force cod liver oil down my kids' throats. They did not enjoy that." Nor did I when I tried to show them that it wasn't that bad. So, but I tried it and that's my preferred method of taking them. So, three a day. How much wild arms is in each dosage, which three capsules are dosage, right? Two drops of gas. Okay, so we're getting about six drops. Okay. So, it's important to recognize that when people talk about fish oil, we've all tasted or smelled bad fish. It's hard to breathe. You take care of people like, "I don't know, Havana." Right. A high quality fish oil, especially the ones that we get from the Nordix use through the manufacturing process that we use, is an extremely cheerfully handled fish oil. You can actually, like you just said, put it in your mouth and chew it. If you taste fish, yeah. And that's right. Gone right. Right. The fish market. And if you don't smell something other than the ocean when you smell the fish that you're buying. Old rancid fish. So, high wool fish oil is a good experience. You could use it as a salad oil. It's so delicious. You could use it anywhere you want, right? You could use it in cooking. But poor quality fish oil, which is vast majority of the market out there. People have real negative experience. Talk about how it gets fish burnt. Yeah. It's terrible. We don't get any of that with these. I don't, anyhow. Well, it's all, you really don't. Yeah. Fight those capsules and have such an easy thing. And I love it. Yeah. Such an easy thing. And so, even my grandson, we've poked those capsules. Obviously, we don't want them have the capsule because, you know, that we poke it and give him, like, one a day, you know, he's two. He loves it. And when, before he could talk real well, he would be, like, more, you know, in sign language. And he would, like, keep trying to give us more and more and more. But, kind of going to that question, can you overdose on fish oil? Yeah. Of course. You can overdose on anything. You can overdose on water, right? Yeah. But, highly unlikely. But I do love your idea of children in a zero to six, seven years old, one capsule, eight, over about the 18 years. Yeah, that's awesome. And I know early on, we did some testing on, like, where omega levels are. Mine was, I've been supplementing on omegas for many, many years. And I was kind of shocked to discover I was actually below. And it was recommended that I take a few more to try to, like, get that level up. Is that something you would recommend people to kind of check out? Or do you feel like the three is sufficient? I still hope. I, I want to today, when do Terra has that, that's available for every use on a regular. Right. I think that it's very useful that I'm the sort of person that does not like to start driving my car until I know exactly where I want to go. Sure. And I think that data helps us do that. So I do not get out Google Maps and say, take me in. Yeah. I, I really want to know where I'm going and I want to hit that target. And, and so using these blood tests that are just fingerbert, blood. Generally, you can do Venus punctures and get other levels where really reliable methods now that just take a fingerprint. You put the blood on a card, send it in and it'll send you back your, your level. That's a tremendous in helping people know exactly where there are and where they should be. And everybody that we used that test with in our trial for EO plus had dramatic increases in their EO mixed blood levels. So not just most people. Yeah. Three single trial participants saw a dramatic increase in the what will begin. So it could even just have been the quality of the soil that I had been taking prior to the test store, whatever. And so. And could be amount of the particular EO mega BHA and DPA and and every what there's multiple different omega fatty acids. Okay. The ones that are cardio protective, the FDA has made a very clear need to be at certain levels and so let's make qualified help claims about that. And our art at those levels and we don't just formulate to it, we test to it, they that we put in is actually there. So I don't think that the fish oil supplement industry is as rigorous as it needs to be. Sure. Sure. I know Doterra's standards are very high. A question on the study of the Omega's that you did. How long was that they got to see the significant increase? We did that EO mega study over a six week period of time. If memory serves spinning here, but I think that was the study. That's not that long really to get an increase. So that's exciting. That's exciting data. So if someone is taking just a fish oil from, you know. I don't know their local local place, their local anywhere or Walmart or picking it up off the shelf. What would you recommend for them? Should they switch? Should they look at adding wild orange to it or what is your recommendation? No, I think that the recommendation that I have is that we take enough EPA and PhD to have our blood levels at a certain cardio protective level. I would recommend knowing what your level is and shooting for that level that you want to be at. Right. I know EO mega plus better than any other supplement on the market and I strongly recommend it. I know exactly where it comes from and what's in it. Right. So I'm very comfortable with that. I think that I would do a couple of things if I were taking official supplement and trying to decide whether or not I wanted to switch EO mega. Yeah. I would try tasting your fish oil. Yeah. Whether at what level your fish oil tastes like fish? If it tastes fish, it's answered. Yeah. You're not getting the benefit or you're the bang for your buck if you will. And then I would side by side compare that with the taste of EO mega plus. And I think that will help people see the difference or feel or taste the difference. Right. Get a good idea. If somebody's married to or wants to use what they had, just adding wild orange oil to their fish oil regimen or to their smoothie in the morning, would be a great way to gain the benefits of the speed that I was describing. Yeah. That's a really good recommendation. Do you add any extra wild orange to your daily routine? Nope. Your six drops is sufficient for you. I mean, that's a lot of exxgenes expressed, right? If I'm using the right terminology, just by taking that amount, is it still blows my mind? Urban 900. They're using AI and machine learning right now to understand where those 940 unique to the limony group to the wild orange group, how they interact with one another. So fascinating. I love it. I love it. Well, I feel like we really dabbled and got into deep enough for everybody to understand Omega's. And hopefully that will help everyone get stronger hearts and protect those hearts. So the next biohack that we're going to move into is Copaiba. Copaiba. It's said multiple ways like tomato tomato. I always say Copaiba. But. What do you do that if you go to Brazil? Don't do that. So what's Brazil? Copaiba? If it's a Brazilian treat, rape, and treat. And so if we want to be kind of ethnocentric or appropriate, we would say Copaiba. Okay. That is the correct way to say it. Correct. And you're aware that I get corrected about saying that when I enter Brazil this past year. Oh, that's awesome. Now I'm sure they're probably like this guy doesn't know what he's talking about. There's only one way to say it. So Copaiba. I have to go, but I actually used to say it that way. And then I thought we were taught to say it the other way. And it's like, I'm like, I don't know what to say. I'm just telling you that it is a Brazilian treat. And maybe we should just say it. We'll say it. I'm good with that. I'm totally good with that. This study is phenomenal. There's a couple of parts to it. But it's still like blowing my mind on the fact that we can literally just take a few drops of Copaiba. Well, it has to do the soft gel. We talked about that. Not sublingual. That's how the study was done. I guess we don't fully know. Yeah. I want to do something. What probably will be the right. Yeah. We don't know. Right. We just don't know. But a 32% increase in core strength without exercising. Like, it's like a dream. 15.3% increase in functional movement, all we get. Crazy. Crazy. I mean, microbiome, so much stuff. Yeah. Break down this study. It wasn't a very large study. It was only a couple of dozen people. But when we looked at the people that were in the study, we used a blinded physical therapy group. So the physical therapy group did not know what we were doing and they were measuring. They were just measuring people before and their functional movement capacity before taking the supplement and their functional movement capacity afterwards. And just a matter of weeks, we saw people's functional movement improve 18.3% in the study time period. Which was, let's a remarkable finding. Very. The most impressive finding was this 32% increase in core strength. Yes. Remarkable. But if you think about the supplement itself, Copaiba is an essential oil derived from a tree in the Brazilian rainforest. And this tree, this oil comes highly with a high level of beta-caryophilic, which is a molecule that binds to CB2 receptors in the body. These are the same receptors that CBD binds to. And so when receptors are bound and activated, cascade of events occurs inside the cell that are triggered by that particular receptor. So when you bind to the receptor, you get this waterfall cascade of things happening inside the cell. Gene expression changes like we've been talking about. And so whether you're bound by CBD or you're bound by beta-caryophilin from Copaiba, the effect is relatively going to be similar. So when we see CBD has long been known to improve people's appetites and used to help people with muscle-wasting problems and all sorts of issues, and we saw in this group of healthy pecor. That there, when we use beta-caryophilin in Copaiba, their functional movement improved. Pretty remarkably, this was a statistically significant -- to be out of small sample size. It was statistically significant, and of course these percentages were clinically certain. So we saw them with squats, with deep lunges, with shoulder, neck, back, core strength. It was a really remarkable thing that we were at the measure. Yeah, and just to help our listeners understand, these were not athletes. Like you said, they were just, you said 12 individuals. We weren't working out between -- they had this core strength done and all of these functional tests done on day one. And then you gave them a Copaiba soft gel, once in the morning, once at night, or once off gel twice a day, something like that. Soft gel twice a day, morning and night. For 30 days, right? And then you had them repeat the exercises at the end and found out core strength is like over 30% better without exercising. And then all of the other ones had, you know, you said 18% overall. Yeah, we were kind of pleasantly surprised. It was cool. That's fantastic. Right. But we have the biological plausible reasoning as to why when we understand what the receptors are activated in the cells. And we know that CBD is longer than used for similar. So it makes sense. Yeah, absolutely. So, I mean, obviously these people weren't working out. But with -- if you have someone who is actively working out every day, I mean, I can only imagine that it would enhance that as well. And then there was also -- there was a study on microbiome and just by taking the same study, okay. And it was statistically better. So, strains? So we looked at people's microbiome before taking the supplement, but could be the supplement, and afterward. And compared the relative concentrations or percentages of different strains of bacteria. And what we saw were that three specific strains of bacteria involved in guterate production. Reuterate being something that helps with the integrity of the gut wall or gut. As well as altering the microbiome of the gut itself. Reuterate has long been shown to improve the help the bacteria in your gut and decrease the potential problematic bacteria in your gut. These three strains of bacteria were statistically significantly increased and people taking the co-pibus supplement. Which was a remarkable finding for me, because I -- Yeah. -- it's a Z-Doc. And I did not anticipate that a chemical would -- like beta-cariofflin -- or an essential oil, which is a verautomation, a naturally complex substance with multiple chemicals in it. I think that chemistry could be smart or intelligent, but it was. And it changed our microbiome in a broken way. It's a remarkable finding for me. I loam somethings out there. I mean, I feel like I did, too, because I feel like I only would think that a probiotic or culture, yogurt, or cottage cheese, or butter, like whatever that would have to help colonize the integrity of that digestive system and gut lining. And it's just incredible. It was the first essential oil microbiome study of the time nobody had ever done it. Oh, really? I know. You guys did some really fantastic studies. Did they mention if their digestion felt better or they did? Yeah, we did digestive surveys on all of them. These are surveys that are clinically validated, certain, to measure the help rate digestion. Do you think there's a connection between gut health and the muscle? Or -- What I can tell you is what we know about those CB2 receptors. Is that CB2 receptors are in the gut. They're also in our smooth muscle and our skeletal muscle. They're in our heart. They're all over the body. Okay. So you're getting a benefit. Yeah. Whole body benefit. So body composition. It was 3% less fat, 3% more muscle. No weight change, right? Now you've moved on to the foundational wellness. Oh, wait. Okay. I might have moved. Okay, but that's right. That's right. We didn't do the BMG yet. We'll save it. Yeah. You want to save that till we move into BMG? Or do you want to explain it now? Whatever we'd like to do. I mean, we could do it here. It's easy. Okay. Let's do it here and then we'll transition into the foundation with the BMG. So you're referencing this body composition data that we got this past year in a clinical trial where we took around a hundred people and half of them received three supplements that we call our foundational wellness supplements, our Eomega, the MG and Kibi Restore products. And the other group took those same tree supplements but added to it the Copaiba soft gels. Okay. So when you compare these two studies, you're basically doing a Copaiba study. So you're looking for what is the difference that Copaiba offered. Right. And look to people in the Copaiba, Copaiba group, what we saw was phenomenal. And the Copaiba group saw a dramatic improvement in long-term, short-term memory as well as executive function. So all three of the memory-based assays, so these standardized surveys that we do to look at short-term, long-term, and executive function or clinical or brain health. All three of them were statistically significant in three. They should have Copaiba. Then we noticed that in the group, you remember in that Copaiba study we referenced earlier where we were probably Copaiba alone, people seemingly got stronger. Their function, their movement increase. In this study we looked at their muscle mass and their fat max. And we saw a body composition change in a one-for-one exchange where we lost essentially 3% body fat and gained 3% muscle mass in the Copaiba group. This was not experienced in the group that did just the three supplements without Copaiba. Wow. It is only with the addition of Copaiba that we saw that one-for-one exchange with fat, extruded from muscle. That was a remarkable finding because we know, we know after long decades of research that muscle mass equals longevity and health spent. Yes. It is an extremely tightly linked thing. Use it or lose it. And the more muscle you have, the older you are, the healthier you will be, the more joy you'll get out of those years. Because the food the things you want to do, because you have the muscle mass to do it. Right. So, definitely all have to go out and become Arnold Schwarzenegger. Yes. I love it. That is incredible. Now, these participants, these 100 participants weren't just starting a new workout routine either, right? Like, they were just. Yep. They were all just living their life, their normal life. Yep. Not doing anything special. So, just imagine upleveling it by starting a weightlifting routine. Not doing anything crazy that your doctor wouldn't recommend, but just initiating some movement. Yes. Yeah. It will be synergistic for you, I believe. And I think that it's important to stay, though, that this one-for-one exchange, people didn't lose weight. We're not talking about a weightlifting routine. Right. Right. We actually saw them exchange that for muscle. Which is body recomposition, right? Body composition. Yeah. Yep. How long was that study? How long did you. It takes that. Three months. So, in three months, they had a 3% one-for-one exchange from body fat to muscle mass, not weight loss, but. Yeah. The muscle does tend to weigh more than fat, so you're almost surprised they didn't gain weight. I think it's me-waking, it's the same, but you can see that exchange. Yeah. This phenomenal. I love that. One other thing you said on our last chop that we had was that 75%. And we're kind of. We're pivoting over to our VMG product, part of that foundational wellness. But we were talking about foods and things with longevity. And you said 75% of our food comes from 12 plants and 5 animals. So, how terrifying is that for longevity, right? But let's deep dive a little bit into VMG and talk about absorption issues. I mean, many people are supplementing and looking to supplements, and they're really just peeing them out, and they're just going through them in two hours. Let's talk about why VMG is 400% more bio-available, white stain, or system longer. What's wrong with regular vitamins? Some of those things that people tend to maybe choose not to even supplement, because they're like, "It's a waste of money, I'm literally peeing my money down the drain, right?" It's not that it's a waste of money, it's just that it's old technology. Yeah. Vitamin technology then arouses the mid-19 fourths. Wow. Our diets needed supplementation for decades and decades. But there are vitamins that are basically unchanged from the 1945 formula I live or sold spit. Wow. And that makes, like, no sense, considering the amount of scientific breakthroughs, and I understand that we have, around physiology and the organ function, specifically within our bodies, and how these vitamins actually work for us. So the recommended daily allowance of vitamins is actually decades old. It's a recommendation based on the absorbed capacity of an individual human being, as well as the technology of vitamin used. Right. So I had a doctor tell me that RDA, or recommended daily allowance, stands for really dumb advice. And I kind of think that's true, I mean, vitamin D, you know, Utah, where I currently am, at our northern latitude. You might get enough sunlight. Right. We should all be supplemented with vitamin D, and the levels of supplementation that most vitamins have are quite low. Sure. Lot's story short, vitamins, there's nothing wrong with vitamins. Vitamins are very, very important in our bait life, because we get most of our food from a very monochromatic palate. We just don't have the variety that we used to when we all had badly farms. Right. And we were hunting and gathering for our subsistence. Today we just go to the grocery store, and the other thing that's wrong with grocery stores is that we have bioengineered, leach neared, or bread, apples that have shell stability for six months. It's crazy. And they look really, really great. They look great. Treat. And that's actually the phytonutrients within those really shelf stable, sexy looking vegetables and fruits are not what they were. Right. Back in the 1930s and 50s when you didn't have those strains and species. Sure. And so we've genetically engineered a lot of the phytonutrients out of our food. So, eat your food that is just relatively less full of what we need. So supplementation, if that's the case for supplementation, that's the case. If you're not convinced that you need a supplement for vitamins and minerals after that discussion, I can't help. You have another problem. So, we have a need. I want to use technology that is based on 1950s technology or something that's a little more current. G is the most technologically advanced vitamin supplement on the market. It contains both vitamins, minerals that are essential and greens. All three of these have been shown to be incredibly important for our longevity and our health. So, there's a reason why phytonutrients are phytonutrients have the name that they do. We want the enough of them. Right. So, we package these vitamins in DMG and we use liposomal technology. We use essential oils. We use methylation technology for the B vitamins. All of these are designed. All of these technological advances are put into BMG to aid in something we call bioavailability. Bioavailability is what percentage of the vitamin that I put in my mouth and into my stomach actually gets to my body and is there to be used. Bio retention is how long does that vitamin or minerals stay in my blood, available to my body to use. He uses technology to make the vitamins about on average, about 400% more bioavailable than for technology vitamins still on the market today. Sold in Costco, sold all of these vitamins are everyday. And BMG is about 400% more bioavailable. And most vitamins, these vitamins go in and out of your bloodstream within about two to three hours. He have G's vitamins stay out longer than eight hours in your blood, thereby being available to your organs and cells to use when you need them. Right, right. Because you might not need them for that first two hours. You might need them on hour four, right? Yeah. Or after chasing your friends. Yes. And if I'm right from what I heard from that study, they just ended that study at eight hours. They don't really know if it could even be longer. Is that correct? I always take this off with that study because I copped like twice as long as regular would be sufficient. But we actually don't know if we didn't pass that eight hour mark. So it'd be really nice to know if 24 hours, not much of that. It's insane though. That's very exciting. Just eight hours is great. I know that because if I've forgotten to take it and it gets to be two o'clock in the afternoon, I'm well aware of it. I forgot something in my day and I can trace it back to that. So good. Some of the clinical outcomes was supportive of the thyroid and A1C levels. That's huge for aging, right? Helping with inflammation. foundational wellness. Yes. National wellness route included BMG. Okay. And keep you restore. Okay. Door being our microbiome. Okay. These are class meters. Mm-hmm. In their vitamin space, BMGs. So this wasn't part of that ko-pa-iba. Yeah. Okay. Did they have ko-pa-iba for that one too? Okay. No. No. Okay. Different study. Okay. It see these changes, but. Okay. But these are the study that you're describing the thyroid stuff. That was on. Okay. Okay. Was those PB assist? BMG any omega? PB restore. Okay. You'll make a plus in BMG. Okay. How do you keep these studies straight? They're so messy. So many conversations. I bet. I bet. We're on our DNA. So this study looked at all three of the supplements used together over a three month time frame. Okay. That we saw that it rewrote our metabolic thermostat. So everybody has a metabolic level. If you heard of my fast, I have fast metabolism. I have slow metabolism. Right. Right. Right. So when we give the body more of what it needs, the body functions at a better level. And one of the ways we measured that was showing that thyroid hormone went up. And TSH levels went up. Meaning that we were stimulating the thyroid to increase your body's thermostat to turn up the volume. Increase your metabolism. Improve your metabolism. Nice. That was something we saw. And then A1C, was that the. Yeah. So the A1C in that study group came down. And this also is a metabolic. These were all healthy people. None of them were pre-diabetic. None of them did eye back. Right. We saw both the levels of A1Cs humming to her. Knowing that new hosts is. Mm-hmm. Right. And water. It is. Let's see. Okay. Mm-hmm. We are already. We are full. Now, our protein is on the day. I just coxidize. Slowly, slowly, slowly. Right. One of the ways we age. Mm-hmm. Oxidization of our proteins. Okay. Increases that oxidization. Yeah. It's like caramelization. It's delicious, but it's a devil. Me, another of the holidays. Right. So it's great, but it sugar is an ageer. Mm-hmm. For ages us. Yes. When A1C comes down, that means that your circulating blood sugar has been lower over that three-month timeframe. Mm-hmm. And you're exposing your body to less of that oxidizing. That's awesome. So who would need this most? Who do you think should be on supplements? The foundation of wellness? Human being. Yeah. Everyone can benefit. Yes. Oh, my gosh. It's a function of modern life. There's about modern life that I would. Modern life is so amazing. And it used to have one billion people on it. Now it's got billions and billions. Mm-hmm. Why? Because we've been able to grow lots and lots of food to feed us. We've been able to package things, make things shelf-stable, refrigeration, all these technological advances. I'll allow for human beings to have the life that you have today. Cell phones, computers, you and I are doing the podcast. Right. Unconceived. You're in Utah. I'm in Pennsylvania. And you're just talking. Yeah. And that was stuff that was Star Trek-esque. Right. Oh, just a while ago. But modern life comes with a cost. Yes. Yeah. And so everybody's living in modern life. I don't care. Yeah. Right. How off the grid you are. The food industry, it is what it is. Yeah. So I think that these supplements are a secret weapon. And manage, overcome, I'm not sure what the right idea is. Yeah. You have effects of modern lifestyle on our health and wellness. Yeah. Mitigate might be the best one. It mitigates the effects of a modern lifestyle on our health and wellness. Right. To live our healthiest life possible. Yes. That's what we want. We want to be able to live as healthy and do the things that we love. You know, we've looked at those charts of how chronic disease. You know, you're not living very well for the last 10 years. Because we stay alive, but we don't stay alive well. We want to live well and then drop off. Right. That's not living. It's existing. Right. No. This has been so good. Now, finish up here. If someone could only afford two of the supplements we talked about today, what would be your two favorite? It depends on the person. Okay. That makes sense. Oh, important. That's helping. Yeah. So you need to walk them through their biggest problems are. Right. Somebody has digestive issues. Keep you restored. Maybe essential. We haven't talked much about. Sure. She's keep you restored and they'd be really important. Yeah. Somebody's energy level or sleep or you need to help people they specifically need. The two that I think are most universally applicable, if I was to generalize and not be specific about an individual, would be VMGME Omega Plus. Yeah. Those two right there are major biohats, things that are going to impact sleep, cognition, aging, energy, drive. And they have essential oils in them. These are essential oil powered supplements, right? So they're getting their essential oils in there. They're getting so much. I mean there's just so much. And a little bit of probiotics are in the VMG, right? Like there's a small. Yeah. Yeah. Yeah. Yeah. Yeah. Perfect. That's where where I would be. Okay. I love it. I think that's very spot on too. Are you comfortable sharing your own personal daily routine on what you do every day? Yeah. What's a woman's you take? So I'm a, I use conditional wellness every day. So gee, make a awesome beauty restore. Although I do them it's slightly different times. Okay. The way that my I've structured my line. Sure. By theme G and E Omega in the morning and my beauty restores of my, because there are other things at night that surrender these sacchares and stuff. Yep. That I put together at night. I use the recharge with their cat that I do. Yeah. So I've recently as a, as a not so younger man. My own practitioner physician tell me that muscle loss is really important. I have to be a way lifted all during your life. We're going to have to start doing that. Yeah. It's a week. I want you to live. Well, can I tell you right now that this thing? Do you hate it? I know. I think I did. I've been doing it for a while. I'm the same. Just similar. We're long and lean. We're tall. Yeah. I'm never. Because I'm full. Yeah. Well, yeah. They don't be killing for all the time. Right. When I use recharge, I feel less sore. Yeah. Nice. Workout. So my daily routine includes as well 30 minutes to 40 minutes of cardio every day. Wow. Three days a week. I add another 15 to 30 minutes of lifting depending on what part of the body I'm working at. For every one of those workouts, I'm in a sauna for 20 minutes or 100 minutes. Good for you. Very good. Love it. And you do the sleep supplements. You said. Okay. And I was assuming you do the Copaiba. I use her as I'm pretty much every day. Yeah. Lavender all the time. Mm-hmm. I'm using sandalwood. Mm-hmm. Love sandalwood. That sounds amazing. I know. We love our sauna too. It's so good. Now thank you for sharing that. There's so many other things I do on camera. Well, I was diffusing. Yeah. And then diffusion is just constant. Right. We don't even count that in as part of our daily thing because it's just, it's about it like brushing your teeth. Oh, awesome. So let's see. I have a couple more rapid fire questions and then we will close out. What biggest longevity mistake people make? Not movie. Oh, fair. That's so simple too. Simple to do. Simple not to do. Okay. So the biggest mistake people have, you know, is just thinking that they can biohack their way out of me. That makes perfect sense. And such a simple thing to do. And like I said, not to do. What are you researching? You want to walk with somebody you love and fucking out of life and not talk about stress. Right. Next with somebody on a walk for 20 to 30 minutes every day. And your life will improve. Improve. That's so true. Just being outside is just, oh, we event such cold weather here. And I was telling the girls and I walked in. I was like, oh my gosh, I just want to, I don't want to just podcast this like 60 degrees outside. Like we got a free spring day in January. It's crazy. Love being outside. But what are you researching next if you're allowed to share? We are doing a lot of single oil research studies. Fun. I'm coming. So we're looking at a lot of things that will, I think, be very important before. And our understanding of central wars in their uses with some really exciting substantive claims to be showing true, both genetics and traditional biological outcomes. The study. They're, they're the major. That's exciting. When, when do you think we'll maybe hear more about that in September maybe or. Yeah. September. That's exciting. Okay. So do you think 100 is the new 80? So when we're, is that, do you think we're, we're moving towards that? Yeah. Yeah. It will only be, it will only 100 will be the new 80. Only for those who advantaged themselves of a technology of this stage of our existence. Right. We do not take advantage of the technology that is available to help us. 80 will still be 80. People are going to get overweight, they're going to eat themselves to that metabolic disease. It's a plague amongst us. And if we do not take care of that, I'm 80 will remain 80. Yeah. But if we are mindful, if we are advantaging ourselves of our scientific or medical advances that allow us to live a healthier life than yes. 100 will be the more aid. I love it. I love it. That's exciting, because you know, we're all just getting older. Is it, is anyone too old to start some of the implementing some of these things biohacks we talked about? That's one of the most amazing things about human body. Is that the human body does not seem to care when we decide we're going to take care of it. It will always respond positive. You may add, I get as much bang out of the box as you do. Best be much early in your body's health. You invest. You will improve. The body wants to be helped. It may help be choices. The body will respond. Or respond. I love it. Any or none. Yes. I love it. I love it. So for someone who's listening, who's skeptical, who's maybe heard of essential oils, heard of supplementation, and they're just like, I'm just going to listen to this guy. See what he's researched. What result he's got. What would you say to them? Is there still skeptical? We'll join it up. Yeah. I'm highly skeptical of this industry. As a doctor from the medical profession, infectious disease. I mean, I'm sure, yeah, like you had lots of suspicions. I'm still attending. So I take care of kids and I see ease all the time. But I've done this research. This isn't somebody else's research. This isn't the research that I bet. It's not that I believe it is that I know. I'm no longer skeptical about the things that I've talked about today. I have the research to back it up. Everyone I think comes, Jen, when people try to sell something and sell the research as more than it is. Like you asked me multiple times today, well, does it allow you to say this or does it do this? And I have to say, I don't know. Right. Know what all I can tell you is what the research is told me and what the data says. Right. I think that this industry sometimes gets a self into trouble by going too far. Sure. Taking things too far. If I take serenity for 12 weeks, will I gain 14 years? Right. Yes. So we shouldn't say that. And we need to be careful when we share this data to do so in a manner that is both intellectually honest and appropriate. Scientifically power. That's necessary and needed in my mind in our industry. Right. It is making a contribution. There is very little data like the type of data I've described on essential words. There's good data on some supplements. But on essential oils, there's just not as much of a database perspective. We are adding to that on the daily. And I'm going to spend the rest of my career doing it. I love hearing that. We are so lucky to have you at the Otera. And because you do do that so beautifully, you do the research. You teach it well. Like I said, I've been so obsessed with this presentation since you taught it for our private group. And I was just like, I would listen to it over and over. And I'm like, I cannot teach this like Dr. O. I know you say we can, but it's just you do such a beautiful job. Because you do know the research and you do it such beautiful justice. But yeah, I mean with that, thank you so much for sharing. We kept you longer than I thought we would. Because I was like, I'll just keep talking to him and learning all of this stuff. You just have so much to share. And so just thank you so much for taking the time for our listeners and for our audience. And so we would love to have you back sometime. And anytime it's precious, so it might be a year or a year or a half so I can maybe get you back. But with that new research, I'd love to hear from it one-on-one with you again. But yeah, so. Jen, thank you for the opportunity. Good luck to have you here in 2026. I hope it's a good one. Yes, I love it. Thank you so much, Dr. O. If you like this content, please give us a like, subscribe. And if you have any questions for us, just drop a comment below and we'll be sure to follow up. Thank you for joining us today.